Regeneração de atrofia de substância branca após a cirurgia de epilesia: evidências estruturais através da morfometria baseada em voxel / Recovery of white matter atrophy after epilepsy surgery: structural evidences through voxel-based morphometry
J. epilepsy clin. neurophysiol
;
15(1): 07-11, mar. 2009. ilus
Article
in Portuguese
| LILACS
| ID: lil-523213
ABSTRACT
OBJECTIVES: To study pre and postoperative WMA in MTLE patients. METHODS: We performed Voxel-Based Morphometry (VBM) with volume of interest (VOI) in 69 controls (mean age, 34.3±11.1 years) and 67 operated patients (mean age, 34.1±10.4 years) with unilateral MTLE. 34 became seizure-free (SzFree-Group), 23 improved (Engel IB-IIA [Partial recovery-group]) and 10 did not improve (Engel III-IV [Failure-Group]). All had pre and postoperative MRIs (one year minimum). We flipped MRIs of right MTLE patients in order to avoid right-to-left analysis cancelation. VBM was performed on SPM2/MATLAB7.0 with individual masks for surgical lacunae and 1 percent false-discovery-rate to control for multiple comparisons. We used MARSbar
Full text:
Available
Index:
LILACS (Americas)
Main subject:
General Surgery
/
Epilepsy
/
Epilepsy, Temporal Lobe
/
White Matter
Limits:
Humans
Language:
Portuguese
Journal:
J. epilepsy clin. neurophysiol
Journal subject:
NEUROCIENCIAS
Year:
2009
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
UNICAMP/BR
/
Universidade Federal de Lavras/BR
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