Bioactivities of extracts from the marine sponge Halichondria panicea
J. venom. anim. toxins incl. trop. dis
;
15(3): 444-459, 2009. ilus, tab
Article
in English
| LILACS, VETINDEX
| ID: lil-525813
ABSTRACT
In the present study, we screened the biological activity of extracts from the marine sponge Halichondria panicea collected in the Arabian Sea. Crude toxin was obtained by methanol, chloroform-methanol (21) and aqueous extraction. Subsequently, the protein concentration of each crude extract was determined. The impact of both sponge methanolic and aqueous extracts was found to increase activities of Na+-K+ ATP-ase and Mg++ ATP-ase. In the case of chloroform-methanol extract, higher concentrations increased acetylcholine esterase (AchE) activity. The methanolic and chloroform-methanol extracts exhibited hemolytic activity on chicken and human erythrocytes, whereas the aqueous extract failed to do so. Methanol and aqueous extracts produced an immunostimulating effect and all extracts revealed angiogenic activity. The aqueous extract yielded nine bands by SDS-PAGE on 12% gel.(AU)
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Porifera
/
Biological Products
/
Marine Environment
/
Adenosine Triphosphate
/
Electrophoresis, Polyacrylamide Gel
Limits:
Animals
Language:
English
Journal:
J. venom. anim. toxins incl. trop. dis
Year:
2009
Type:
Article
Institution/Affiliation country:
Central Institute of Fisheries Education/IN
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