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Allogeneic transplantation in multiple myeloma / Transplante alogênico no mieloma múltiplo
Majolino, Ignazio; Severino, Alessandro.
  • Majolino, Ignazio; Ospedale S. Camilo. Institute of Hematotherapy. Hematology and Stem Cell Transplantation. Rome. IT
  • Severino, Alessandro; Ospedale S. Camilo. Institute of Hematotherapy. Hematology and Stem Cell Transplantation. Rome. IT
Rev. bras. hematol. hemoter ; 31(supl.2): 35-40, ago. 2009.
Article in English | LILACS | ID: lil-527521
ABSTRACT
In this review the authors present a state of art tretment of multiple myeloma.High dose chemo-radiotherapy followed by autologous hematopoietic stem cell transplantation has been show to be superior a conventional chemotherapy and a double transplantation. The authors discuss too, the allogeneic transplantation with reduced intensity conditioning, allogeneic versus tandem autologous, results the patients long term outcome and a approach about the use of donor lymphocytes, anti thimocyte globulin and a overview of post transplant therapies.
RESUMO
Neste relato os autores apresentam uma revisão sobre o estado atual do tratamento mieloma múltiplo. São enfatizados aspectos sobre a vantagem do transplante autólogo em seguimento à quimioterapia convencional e o duplo transplante. São discutidos o transplante alogênico e o condicionamento com intensidade reduzida, além do uso de linfócitos do doador, da globulina antitimocítica e uma visão geral do futuro da terapia da moléstia.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Multiple Myeloma Language: English Journal: Rev. bras. hematol. hemoter Journal subject: Hematology Year: 2009 Type: Article Affiliation country: Italy Institution/Affiliation country: Ospedale S. Camilo/IT

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Full text: Available Index: LILACS (Americas) Main subject: Multiple Myeloma Language: English Journal: Rev. bras. hematol. hemoter Journal subject: Hematology Year: 2009 Type: Article Affiliation country: Italy Institution/Affiliation country: Ospedale S. Camilo/IT