Marine Pseudomonas putida: a potential source of antimicrobial substances against antibiotic-resistant bacteria
Mem. Inst. Oswaldo Cruz
;
104(5): 678-682, Aug. 2009. ilus, tab
Article
in English
| LILACS
| ID: lil-528072
ABSTRACT
Bacteria isolated from marine sponges found off the coast of Rio de Janeiro, Brazil, were screened for the production of antimicrobial substances. We report a new Pseudomonas putida strain (designated P. putida Mm3) isolated from the sponge Mycale microsigmatosa that produces a powerful antimicrobial substance active against multidrug-resistant bacteria. P. putida Mm3 was identified on the basis of 16S rRNA gene sequencing and phenotypic tests. Molecular typing for Mm3 was performed by RAPD-PCR and comparison of the results to other Pseudomonas strains. Our results contribute to the search for new antimicrobial agents, an important strategy for developing alternative therapies to treat infections caused by multidrug-resistant bacteria.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Porifera
/
Pseudomonas putida
/
Drug Resistance, Multiple, Bacterial
/
Gram-Negative Bacteria
/
Gram-Positive Bacteria
/
Anti-Bacterial Agents
Limits:
Animals
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2009
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Museu Nacional/BR
/
Universidade Federal do Rio de Janeiro/BR
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