Prevalence of the precore G1896A mutation in Chinese patients with e antigen negative hepatitis B virus infection and its relationship to pre-S1 antigen
Braz. j. microbiol
;
40(4): 965-971, Oct.-Dec. 2009. tab
Article
in English
| LILACS
| ID: lil-528182
ABSTRACT
This study investigated the prevalence of the precore G1896A mutation in Chinese patients with hepatitis B e antigen (HBeAg) negative HBV infection and its relation to serum HBV pre-S1 antigen. The overall prevalence of the precore G1896A mutation was 72.6 percent in HBeAg-negative Chinese patients with detectable serum HBV DNA. The prevalence of the precore G1896A is significantly higher in Chinese HBeAg-negative patients with chronic hepatitis B than that in inactive HBV carriers with detectable serum HBV DNA. Serum pre-S1 and the precore G1896A mutation were simultaneously detected in most of Chinese HBeAg-negative patients.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Virus Diseases
/
Hepatitis B virus
/
Prevalence
/
Hepatitis B, Chronic
/
Mutation
Type of study:
Diagnostic study
/
Prevalence study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2009
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
Dalian Central Hospital/CN
/
No.6 Hospital of Dalian/CN
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