Clinical, bacteriological and immunological follow-up of household contacts of leprosy patients from a post-elimination area - Antioquia, Colombia
Mem. Inst. Oswaldo Cruz
;
104(6): 935-936, Sept. 2009.
Article
in English
| LILACS
| ID: lil-529567
ABSTRACT
Follow-up of the household contacts (HHC) of leprosy patients is still the best strategy for early detection of leprosy. HHC from a post-elimination region of Colombia studied in 2001-2002 were re-contacted in 2007. They were tested at both times by clinical examination, bacillary index (BI), PCR from a slit skin smear (SSS) and anti PGL-1 IgM titres. Thirty-two of 61 HHC (52 percent) were re-contacted. Nine HHC (28 percent) showed sero-conversion and one had a skin lesion (BI negative, nested PCR positive). Periodic evaluation of HHC can contribute to the detection of infected HHC as well as new and early leprosy cases.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Immunoglobulin G
/
Contact Tracing
/
Leprosy
/
Antibodies, Bacterial
/
Mycobacterium leprae
Type of study:
Etiology study
/
Risk factors
/
Screening study
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Colombia
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2009
Type:
Article
Affiliation country:
Colombia
Institution/Affiliation country:
Universidad CES/CO
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