Relationship among epidemiological parameters of six childhood infections in a non-immunized Brazilian community
Mem. Inst. Oswaldo Cruz
;
104(6): 897-900, Sept. 2009. graf, tab
Article
in English
| LILACS
| ID: lil-529570
ABSTRACT
Epidemiological parameters, such as age-dependent force of infection and average age at infection () were estimated for rubella, varicella, rotavirus A, respiratory syncytial virus, hepatitis A and parvovirus B19 infections for a non-immunized Brazilian community, using the same sera samples. The for the aforementioned diseases were 8.45 years (yr) [95 percent CI (7.23, 9.48) yr], 3.90 yr [95 percent CI (3.51, 4.28) yr], 1.03 yr [95 percent CI (0.96, 1.09) yr], 1.58 yr [95 percent CI (1.39, 1.79) yr], 7.17 yr [95 percent CI (6.48, 7.80) yr] and 7.43 yr [95 percent CI (5.68, 9.59) yr], respectively. The differences between average ages could be explained by factors such as differences in the effectiveness of the protection conferred to newborns by maternally derived antibodies, competition between virus species and age-dependent host susceptibility. Our seroprevalence data may illustrate a case of the above-mentioned mechanisms working together within the same population.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Virus Diseases
Type of study:
Health economic evaluation
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Infant, Newborn
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2009
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto de Estudos Avançados/BR
/
Universidade de São Paulo/BR
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