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Etiological treatment of young women infected with Trypanosoma cruzi, and prevention of congenital transmission / Tratamento etiológico de mulheres jovens infectadas com Trypanosoma cruzi e prevenção da transmissão congênita
Sosa-Estani, Sergio; Cura, Estela; Velazquez, Elsa; Yampotis, Cristina; Segura, Elsa Leonor.
  • Sosa-Estani, Sergio; Centro Nacional de Diagnóstico e Investigación de Endemo-epidemias. Administración Nacional de Laboratorios. AR
  • Cura, Estela; ANLIS. Centro Nacional de Control de Calidad de Biológicos. Buenos Aires. AR
  • Velazquez, Elsa; ANLIS. Instituto Nacional de Parasitología Dr. Mario Fatala Chaben. AR
  • Yampotis, Cristina; Hospital San Roque. Salta. AR
  • Segura, Elsa Leonor; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. AR
Rev. Soc. Bras. Med. Trop ; 42(5): 484-487, Sept.-Oct. 2009. tab
Article in English | LILACS | ID: lil-532502
ABSTRACT
The objective was to detect Trypanosoma cruzi infection in 32 children in Salta, Argentina, born to 16 chronically infected young women who were treated with benznidazole. Tests were performed to assess the efficacy of treatment after 14 years. At the end of the follow up, 87.5 percent of the women were non-reactive to EIA tests, 62.5 percent to IHA and 43.8 percent to IFA. 62.5 percent of the women were non-reactive according to two or three serological tests. No infected children were detected among the newborns of mothers treated before their pregnancy.
RESUMO
O objetivo foi detectar a infecção do Trypanosoma cruzi em 32 crianças nacidas de 16 jovens mulheres cronicamente infectadas e tratadas com benzinadol, em Salta, Argentina. Testes foram feitos para avaliar a eficácia após 14 anos do tratamento. Ao final do seguimento 87.5 por cento das mulheres foram não reativas ao EIA, 62.5 por cento ao IHA e 43.8 por cento ao IFA. 62.5 por cento das mulheres foram não reativas de acordo a 3 ou 2 testes serológicos. Nenhuma criança infectada foi detectada entre os recém-nascidos de mães tratadas antes da gravidez.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Trypanocidal Agents / Trypanosoma cruzi / Antibodies, Protozoan / Chagas Disease / Pregnancy Complications, Parasitic / Nitroimidazoles Type of study: Etiology study / Observational study / Prognostic study Limits: Female / Humans / Infant, Newborn / Pregnancy Country/Region as subject: South America / Argentina Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2009 Type: Article Affiliation country: Argentina Institution/Affiliation country: ANLIS/AR / Argentina/AR / Centro Nacional de Diagnóstico e Investigación de Endemo-epidemias/AR / Hospital San Roque/AR

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Full text: Available Index: LILACS (Americas) Main subject: Trypanocidal Agents / Trypanosoma cruzi / Antibodies, Protozoan / Chagas Disease / Pregnancy Complications, Parasitic / Nitroimidazoles Type of study: Etiology study / Observational study / Prognostic study Limits: Female / Humans / Infant, Newborn / Pregnancy Country/Region as subject: South America / Argentina Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2009 Type: Article Affiliation country: Argentina Institution/Affiliation country: ANLIS/AR / Argentina/AR / Centro Nacional de Diagnóstico e Investigación de Endemo-epidemias/AR / Hospital San Roque/AR