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Histopathological studies on the effects of the ethanolic extract of the fruits of Garcinia kola on selected organs of the dog
Nottidge, H. O; Omobowale, T. O; Taiwo, V. O; Omotoso, M. A.
  • Nottidge, H. O; University of Ibadan. Faculty of Veterinary Medicine. NG
  • Omobowale, T. O; University of Ibadan. Faculty of Veterinary Medicine. NG
  • Taiwo, V. O; University of Ibadan. Faculty of Veterinary Medicine. NG
  • Omotoso, M. A; University of Ibadan. Department of Chemistry. NG
Int. j. morphol ; 26(4): 1067-1072, Dec. 2008. ilus
Article in English | LILACS | ID: lil-532935
ABSTRACT
The ethanolic extract of Garcinia kola was administered to dogs to investigate the possible effects on selected organs of the dog. Two doses of the extract (500mg/Kg and lOOOmg/Kg) were daily administered to the test animals for a period of 6 weeks. A dose related response was observed in the severity of histopathological changes observed in the testes, liver, kidney and small intestine of animals in the test groups. Despite the reported potentially beneficial effects of Garcinia kola, its use as a medicinal plant should be with great caution.
RESUMEN
Fue administrado a perros extracto etanólico de Garcinia kola, para investigar los posibles efectos sobre determinados órganos. Dos dosis del extracto (500mg/Kg y lOOOmg/Kg) fueron administradas diariamente a los animales durante un periodo de 6 semanas. Se observó una relación de la dosis con la gravedad en la respuesta de los cambios histopatológicos observados en testículos, hígado, riñón e intestino delgado de los animales. A pesar de los informes sobre efectos potencialmente beneficiosos de Garcinia kola, su uso como planta medicinal debe ser con mucha precaución.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Testis / Plant Extracts / Intestine, Small / Kidney / Liver Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2008 Type: Article Affiliation country: Nigeria Institution/Affiliation country: University of Ibadan/NG

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Full text: Available Index: LILACS (Americas) Main subject: Testis / Plant Extracts / Intestine, Small / Kidney / Liver Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2008 Type: Article Affiliation country: Nigeria Institution/Affiliation country: University of Ibadan/NG