Estimación de riesgo de enfermedad coronaria mediante la función de Framingham adaptada para la población chilena / Estimation of coronary heart disease risk in Chilean subjects based on adapted Framingham equations
Rev. méd. Chile
;
137(10): 1273-1282, oct. 2009. ilus, graf, tab
Article
in Spanish
| LILACS
| ID: lil-534033
ABSTRACT
Background:
Cardiovascular disease is the leading cause of morbidity and mortality in Chile and worldwide. Framingham functions were developed to calculate overall coronary heart disease risk However these functions overestimate the risk in some countries ¡ike Chile. Aim To develop Chilean risk tables to assess the overall 10-year risk of coronary heart disease. Material andmethods:
The Framingham function was adapted for a population aged 35 to 74 years, based on an estimate of Chilean incidence of coronary heart disease and the prevalence of coronary heart disease risk factors such as age, sex, total cholesterol, high-density lipoprotein cholesterol, blood pressure, diabetes and smoking.Results:
The 10-year incidence of coronary heart disease in Chile (2.7 percent in men, 1.096 in women) was lower than the incidence in the United States (10.096/3.896) and Spain (4.996/2.296), but higher than China (1.196/0.496). Framingham tables have more than 50 percent of cells in the risk category of 10 percent or greater. In contrast, Chilean tables have less than 10 percent of cells in the same risk category.Conclusions:
Adapted tables use local information to calculate overall coronary heart disease risk. A validation study should be conducted to assess their predictive power.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Coronary Disease
Type of study:
Etiology study
/
Incidence study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
North America
/
South America
/
Asia
/
Chile
/
Europa
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2009
Type:
Article
/
Project document
Affiliation country:
Chile
/
Spain
Institution/Affiliation country:
Centro de Salud Astaburuaga/CL
/
Institut Municipal d'Investigació Medica/ES
/
Ministerio de Salud/CL
/
Universidad de Talca/CL
Similar
MEDLINE
...
LILACS
LIS