La disincronía cardíaca se correlaciona con el remodelado ventrícular izquierdo postinfarto agudo al miocardio / Cardiac dyssynchrony correlates with left ventricular remodeling after myocardial Infarction
Rev. méd. Chile
;
137(11): 1457-1462, nov. 2009. tab, graf
Article
in Spanish
| LILACS
| ID: lil-537008
ABSTRACT
Background:
Cardiac dyssynchrony is common in advanced heart failure (HF), but the changes in cardiac synchrony after myocardial infarction (MI) have not been adequately descríbed.Aim:
To study the relationship between cardiac synchrony and left ventricular remodeling after acute myocardial infarction. Material andmethods:
Forty nine patients aged 59±10 years (77 percent men) with a first episode of a ST segment elevation MI, were studied. Scintigraphic left ventricular function and synchrony analyses were performed at baseline and after a six months follow-up. Determinations were compared with 33 healthy subjects.Results:
At baseline, patients with MIhad a decreased left ventricular ejection fraction (LVEF) and significant dyssynchrony, when compared with controls. LVEF was 36.4 percent±10 percent, left ventricular end-diastolic volume (LVEDV) 127±38 mL, interventricular delay (IEV) 29±35 miliseconds (ms), and intraventricular delay (IAV), 234±89 ms. After 6 months, LVEF significantly improved (38 percent±10 percent, p =0.042) without significant changes in LVEDV (129±32 mL, p =0.97), IEV (24±17, p =0.96) or IAV (231±97, p =0.34). At baseline there were significant correlations between IAV and LVEF, and between IAV and LVEDV (r =0.48, p =0.001 and r =0.41, p =0.004, respectively). These correlations remained significant after 6 months. There was a positive correlation between IAV and LVEDV changes at six months (r =0.403, p =0.04).Conclusions:
The development of cardiac dyssynchrony correlates with adverse left ventricular remodeling after MI.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Ventricular Dysfunction, Left
/
Ventricular Remodeling
/
Myocardial Infarction
Type of study:
Controlled clinical trial
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2009
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
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