Antinociceptive and bioactivity of leaves of Murraya paniculata (L. ) Jack, Rutaceae / Antinociceptiva e bioatividade das folhas de Murraya paniculata (L. ) Jack, Rutaceae
Rev. bras. farmacogn
;
19(3): 746-748, jul.-set. 2009. tab
Article
in English
| LILACS
| ID: lil-537920
ABSTRACT
The results of antinociceptive and toxicological studies on the ethanol extract of the leaves of Murraya paniculata (L.) Jack, Rutaceae, are reported. The extract (250 and 500 mg/kg dosages) was found to produce a profound antinociceptive activity in a dose dependent manner. The extract showed considerable brine shrimp toxicity (LD50 = 32 μg/mL).
RESUMO
Os resultados dos estudos de atividade antinociceptiva e toxicológicos do extrato etanólico de Murraya paniculata (L.) Jack, Rutaceae são relatados. O extrato (nas doses de 250 e 500 mg/kg) produziu um alta atividade antinociceptiva na forma dose-dependente. O extrato também mostrou considerável toxicidade no teste de Artemia salina (DL50 = 32 μg/mL).
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
Rev. bras. farmacogn
Journal subject:
Pharmacy
Year:
2009
Type:
Article
Affiliation country:
Bangladesh
Institution/Affiliation country:
BGC Trust University Bangladesh/BD
/
Khulna University/BD
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