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Agranulocytosis induced by multidrug therapy in leprosy treatment: a case report
Silva, Itathiana M. C. B. da; Oliveira, Caroline A. P. de; Guedes, Wilma R. C. de A; Oliveira, Benedito Bruno de; Oliveira, Doris Amorim Pontes de; Guedes Filho, Gilson.
  • Silva, Itathiana M. C. B. da; Federal University of Paraíba. Infectious Diseases Service. João pessoa. BR
  • Oliveira, Caroline A. P. de; Federal University of Paraíba. Medicine School. João pessoa. BR
  • Guedes, Wilma R. C. de A; Medicine School Nova Esperança. BR
  • Oliveira, Benedito Bruno de; Federal University of Paraíba. Infectious Diseases Service. João pessoa. BR
  • Oliveira, Doris Amorim Pontes de; Federal University of Paraíba. University Hospital Lauro Wanderley. João pessoa. BR
  • Guedes Filho, Gilson; Federal University of Paraíba. University Hospital Lauro Wanderley. João pessoa. BR
Braz. j. infect. dis ; 13(2): 158-160, Apr. 2009.
Article in English | LILACS | ID: lil-538225
ABSTRACT
Multidrug therapy (WHO/MDT) in multibacillary leprosy consists of treatment with rifampicin, dapsone andclofazimine. However, adverse effects can cause the patient to abandon treatment. We report on a patient whopresented agranulocytosis and hemolytic anemia associated with this treatment regime. We also examined theimportance of laboratory exams for diagnosis and follow-up of the patient, and for early detection of adverse effects, with a view to improving adhesion to treatment and contributing to the eradication of Hansen’s disease as a public health issue.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Agranulocytosis / Anemia, Hemolytic / Leprostatic Agents Type of study: Screening study Limits: Adult / Female / Humans Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Paraíba/BR / Medicine School Nova Esperança/BR

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Full text: Available Index: LILACS (Americas) Main subject: Agranulocytosis / Anemia, Hemolytic / Leprostatic Agents Type of study: Screening study Limits: Adult / Female / Humans Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Paraíba/BR / Medicine School Nova Esperança/BR