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Da mãe África aos filhos Brasil: expressão da herança genética para a anemia falciforme em estudantes docurso de farmácia da Universidade Federal do Piauí / The mother africa children Brazil: expression of genetic inheritance for sickle cell anemia
Soares, Leonardo Ferreira; Melo Neto, Bernardo; Gonçalves e sá, Ciro; Oliveira, Evaldo Hipólito de; Araújo, Bismark Azevedo Cruz de; Veloso, Rafael Pires.
  • Soares, Leonardo Ferreira; Universidade Federal do Piauí. Teresina. BR
  • Melo Neto, Bernardo; Universidade Federal do Piauí. Teresina. BR
  • Gonçalves e sá, Ciro; Universidade Federal do Piauí. Teresina. BR
  • Oliveira, Evaldo Hipólito de; Universidade Federal do Piauí. Teresina. BR
  • Araújo, Bismark Azevedo Cruz de; Faculdade Integral Diferencial. Teresina. BR
  • Veloso, Rafael Pires; Universidade Federal do Piauí. Teresina. BR
Rev. bras. anal. clin ; 41(3): 235-237, 2009. graf, tab
Article in Portuguese | LILACS | ID: lil-544449
RESUMO
Doenca hereditaria de maior prevalencia no mundo e no Brasil, a anemia falciforme ja e considerada um problema de saude publica. Caracterizada pela homozigose do gene da hemoglobina S, acarreta uma gama de sinais e sintomas que exige atencao integral ao paciente. O traco falciforme e caracterizado pela heterozigose do gene da hemoglobina S, ou seja, o sujeito nao manifesta a doenca, apenas carrega a heranca genetica. Na presente pesquisa objetivou-se verificar a presenca do traco falciforme em estudantes do curso de graduacao em Farmacia do Centro de Ciencias da Saude da Universidade Federal do Piaui, utilizando-se a metodologiada eletroforese de hemoglobinas, realizadas a partir de amostras sanguineas previamente coletadas, seguindo-se de questionariosociodemografico, realizadas no mes de setembro de 2007. Como resultado detectou-se a prevalencia de 1,5% do traco falciforme, o que esta de acordo com as literaturas consultadas que indicam a prevalencia de 1 a 4% do traco falciforme nas regioes brasileiras.
ABSTRACT
Hereditary illness of bigger prevalence in the world and Brazil, the sickle cell already is considered a problem of publichealth. Characterized for homozigose of the gene of the sickle hemoglobin, it causes a gamma of signals and symptoms that demands integral attention to the patient. The sickle trace is characterized by heterozigose of the gene of the sickle hemoglobin, or either, the not manifest citizen the illness, only loads the genetic inheritance. The present research was based on the study of the presence of the sickle trace in students of the course of graduation in Pharmacy of the Center of Sciences of the Health of the Federal University ofthe Piauí, having used itself it methodology of hemoglobins eletroforesis, carried through from sanguineous samples previously collected, following themselves of interview half-structuralized, carried through in the month of September of 2007. As result detected it prevalence of 1,5% of the sickle trace, the one that this in accordance with consulted literatures that indicate the prevalence of 1 4% of the sickle trace in the Brazilian regions.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Sickle Cell Trait / Cross-Sectional Studies / Heredity / Genetics / Hemoglobinopathies / Genetic Diseases, Inborn / Anemia, Sickle Cell Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Rev. bras. anal. clin Journal subject: Pathology Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Faculdade Integral Diferencial/BR / Universidade Federal do Piauí/BR

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Full text: Available Index: LILACS (Americas) Main subject: Sickle Cell Trait / Cross-Sectional Studies / Heredity / Genetics / Hemoglobinopathies / Genetic Diseases, Inborn / Anemia, Sickle Cell Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Rev. bras. anal. clin Journal subject: Pathology Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Faculdade Integral Diferencial/BR / Universidade Federal do Piauí/BR