Clinical management of a patient with drug dependence who attempted suicide while receiving peginterferon therapy for chronic hepatitis C
Braz. j. infect. dis
;
13(5): 387-390, Oct. 2009.
Article
in English
| LILACS
| ID: lil-544995
ABSTRACT
Pegylated interferon-alpha combined with ribavirin is the current gold standard treatment for chronic hepatitis C. Illicit drug dependence is not a rare co-morbidity among chronic hepatitis C population, what can make antiviral treatment an outmost challenge. Despite high sustained virological response rate following antiviral treatment, serious psychiatric adverse reactions may occur, like depression and suicide attempt. We report a patient with recurrent depressive disorder, previous history of suicide attempt and illicit drug dependence. We discuss the singularities and challenges of managing this patient in order to complete the antiviral treatment.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Antiviral Agents
/
Polyethylene Glycols
/
Suicide, Attempted
/
Interferon-alpha
/
Hepatitis C, Chronic
/
Substance-Related Disorders
/
Depression
Limits:
Humans
/
Male
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2009
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Minas Gerais/BR
/
Federal University of Minas Gerais+BR
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