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Bases farmacológicas e toxicológicas potenciais do óleo essencial de Mentha spp / Potential pharmacological and toxicological basis of the essential oil from Mentha spp
Peixoto, I. T. A; Furlanetti , V. F; Anibal , P. C; Duarte , M. C. T; Hõfling, J. F.
  • Peixoto, I. T. A; State University of Campinas. Piracicaba Dental School. Department of Oral Diagnosis. BR
  • Furlanetti , V. F; State University of Campinas. Piracicaba Dental School. Department of Oral Diagnosis. BR
  • Anibal , P. C; State University of Campinas. Piracicaba Dental School. Department of Oral Diagnosis. BR
  • Duarte , M. C. T; Microbiology Division. Pluridisciplinary Center for Chemical, Biological, and Agricultural Research. Campinas. BR
  • Hõfling, J. F; State University of Campinas. Piracicaba Dental School. Department of Oral Diagnosis. BR
Article in English | LILACS | ID: lil-549766
ABSTRACT
During the past few years, interest in the potential clinical and pharmacological basis of the efficacy and safety of herbal medicines has increased greatly, due to widespread domestic self-medication with these agents. Some authors have analyzed the use of Mentha ssp. in the pharmacological industry. The essential oil from Mentha spp. is used to treat discomfort of the gastrointestinal tract, irritable bowel syndrome, myalgia and neuralgia, as well as oral mucosal inflammation, and also as an expectorant, an antimicrobial and an ingredient in many analgesic creams. The essential oil also contains chemical compounds that are associated with side effects such as nausea, vomiting, allergic reactions, flushing and headaches. Therefore, the purpose of the present review was to examine the literature on the efficacy and safety of the possible clinical and pharmacological uses of the essential oil from Mentha spp. in human beings.
RESUMO
Nas últimas décadas, houve um aumento crescente no interesse sobre as bases clínicas e farmacológicas potenciais em relação à eficácia e a segurança das drogas produzidas de plantas medicinais, devido à automedicação destes agentes. Diversos autores avaliaram o óleo essencial de Mentha spp., devido a sua larga utilização na indústria farmacológica. O óleo essencial de Mentha spp. componente de muitos analgésicos e com atividade antimicrobiana, é usado para tratamentos nos desconfortos gastrintestinais e dutos biliares superiores, Síndrome de Bowel, expectorante, mialgia e neuralgia, bem como na inflamação oral da mucosa. No entanto, esse óleo contém compostos químicos que apresentam efeitos colaterais tais como náusea, vômito, reações alérgicas e dores de cabeça. O objetivo desta revisão atual foi avaliar dados da literatura específica sobre a possível utilização, eficácia e segurança clínica e farmacológica do óleo essencial de Mentha spp. em seres humanos.
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Full text: Available Index: LILACS (Americas) Main subject: Plants, Medicinal / Oils, Volatile / Mentha Language: English Journal: Rev. ciênc. farm. básica apl Journal subject: Pharmacology Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Microbiology Division/BR / State University of Campinas/BR

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Full text: Available Index: LILACS (Americas) Main subject: Plants, Medicinal / Oils, Volatile / Mentha Language: English Journal: Rev. ciênc. farm. básica apl Journal subject: Pharmacology Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Microbiology Division/BR / State University of Campinas/BR