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Bovine peritoneum protection role on intestinal adhesions to a vascular graft: a morphological analysis / Rol de protección del peritoneo bovino en la adhesión intestinal a un injerto vascular: un análisis morfológico
Uema, Rogério Takeyoshi; Fazan, Valéria Paula Sassoli; Cherri, Jesualdo; Piccinato, Carlos Eli.
  • Uema, Rogério Takeyoshi; University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Fazan, Valéria Paula Sassoli; University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Cherri, Jesualdo; University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Piccinato, Carlos Eli; University of São Paulo. School of Medicine of Ribeirão Preto. Department of Surgery and Anatomy. Ribeirão Preto. BR
Int. j. morphol ; 26(2): 269-274, jun. 2008. ilus
Article in English | LILACS | ID: lil-549945
ABSTRACT
The present study aimed to experimentally evaluate the protection role of glycerin preserved bovine peritoneum (BP) against intestinal adhesions to a vascular graft. Experiments were performed on 24 adult rabbits, randomly dived into two groups. All animals were submitted to a vascular graft over the infra-renal aorta and vena cava. Group 1(12 animals ) was submitted to a BP patch on the retroperitoneal opening, between the vascular prosthetic graft and the intestinal loops. Group II (12 animals ) had the retroperitoneal opening sutured. After 7, 14, 28 and 60 days, 3 animals of each group were randomly killed and the retro peritoneum, with or without the BPpatch, was removed for histological analysis. The histological analysis showed that the BP stimulated a moderate to intense inflammatory reaction at the beginning of the experiments and on the 60-day evaluation, the inflammatory reaction was mild, limited to the BP border with its histological structure preserved. In conclusion, the BP is a safe and cheap interposition material to be used between vascular grafts and intestinal loops, presenting a protection role against adhesions between them.
RESUMEN
El objetivo de este estudio fue evaluar experimentalmente el rol protector del peritoneo bovino (PB) preservado en la glicerina en contra de las adherencias intestinales de un injerto vascular. Los experimentos se realizaron en 24 conejos adultos, randomizados aleatoriamente en dos grupos. Todos los animales fueron sometidos a un injerto vascular sobre la aorta infra-renal y la vena cava. Grupo I (12 animales), fue sometido a un parche PB en una apertura retroperitoneal suturada, entre el injerto vascular y el intestino. Grupo II (12 animales) con la apertura retroperitoneal suturada. Después de 7, 14, 28 y 60 días, 3 animales de cada grupo fueron sacrificados al azar y el retro peritoneo, con o sin el parche de PB, se retiró para el análisis histológico. El análisis histológico mostró que la PB estimuló una moderada a intensa reacción inflamatoria al inicio de los experimentos y en la evaluación de 60 días, la reacción inflamatoria fue leve, limitada a los bordes de la PB con su estructura histológica preservada. En conclusión, la PB es una forma segura y barata de material de interposición para ser utilizada entre injertos vasculares e intestinales, presentando un rol de protección contra adherencias entre ellos.
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Full text: Available Index: LILACS (Americas) Main subject: Aortic Diseases / Peritoneum / Blood Vessel Prosthesis / Vascular Fistula Type of study: Evaluation studies Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2008 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Aortic Diseases / Peritoneum / Blood Vessel Prosthesis / Vascular Fistula Type of study: Evaluation studies Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2008 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR