Novel antiviral activity of dialdehyde starch
Electron. j. biotechnol
;
12(2): 13-14, Apr. 2009. ilus, tab
Article
in English
| LILACS
| ID: lil-551374
ABSTRACT
A significant effort worldwide is being directed toward development of novel biocides against drug-resistant bacterial and viruses because of the significant potential human infection risks in the general population. We report here the discovery of a strong antiviral biocide, dialdheyde starch (DAS). Antiviral tests were carried out against three non-envelop viruses, including two bacterial viruses MS2 and PRD1, and one human virus Poliovirus. Dialdehyde starch aqueous suspensions were effective biocides against these three test viruses in a 1 hr exposure test. The antiviral activity was significantly enhanced in a four-hour exposure test, with maximum seven orders of magnitude reductions against MS2 and PRD1, and four-order reduction against Poliovirus. The antiviral activity of dialdehyde starch was found to be pH dependent, being more active in alkaline and acidic conditions than in neutral conditions.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pesticides
/
Starch
/
Aldehydes
Language:
English
Journal:
Electron. j. biotechnol
Journal subject:
Biotechnology
Year:
2009
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
University of Florida/US
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