Histoplasmosis oral localizada: reporte de un caso clínico en Tucumán, Argentina / Localized oral histoplasmosis: report of one case
Rev. méd. Chile
;
138(5): 586-589, mayo 2010. ilus
Article
in Spanish
| LILACS
| ID: lil-553258
ABSTRACT
Histoplasmosis is an endemic deep mycosis produced by Histoplasma capsulatum, a dimorphic fungus. It penetrates into the organism by inhalation and spreads by lymphatic or hematic route. We report a 57-year-old immunocompetent male presenting with an enlargement of the tongue that also exhibited white pseudomembranes. There were also nodular lesions in the dorsum of the tongue, separated by deep grooves. The pathological study revealed a chronic infammatory process with granulomas. The microbiological examination with the Giemsa technique showed multiple yeasts of 4-5 mm of diameter with a clear halo inside macrophages and epithelial cells, compatible with the parasitic phase of Histoplasma capsulatum. Serology was positive for the histoplasmine antigen. The patient was treated with Itraconazole 200 mg/day, experiencing 40 percent remission of lesions during the frst month of treatment.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Histoplasmosis
/
Macroglossia
Limits:
Humans
/
Male
Country/Region as subject:
South America
/
Argentina
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2010
Type:
Article
Affiliation country:
Argentina
Institution/Affiliation country:
Universidad Nacional de Tucumán/AR
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