Use of the plasma CTX for assessing the bone activity of the mandible among osteopenic and osteoporotic patients
Braz. oral res
;
24(2): 250-255, Apr.-June 2010. graf, tab
Article
in English
| LILACS
| ID: lil-553913
ABSTRACT
The aim of this study was to determine whether the plasma CTX bone remodeling marker is useful for indicating the bone metabolic activity level of the mandible. Thirty-six patients were selected; all were postmenopausal and aged 50 years or over. In accordance with the WHO criteria for osteoporosis, a control group was set up (n = 10) in which the T-score was greater than -1 and a diseased group with T-score less than -1. Using MDP-99mTc samples, the radioisotope uptake in the femoral neck (R2) and mandibular body (R1) was analyzed. A third examination was performed using the plasma CTX biochemical bone-modeling marker. The inferential results for the diseased group showed that Ln(R1) presented a statistically significant linear relationship with Ln(CTx) (p = 0.067) and with the T-score (p = 0.018). The plasma CTX bone remodeling marker is useful for monitoring the bone metabolic activity of the mandible.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Peptide Fragments
/
Procollagen
/
Bone Remodeling
/
Mandible
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Braz. oral res
Journal subject:
Dentistry
Year:
2010
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of São Paulo/BR
Similar
MEDLINE
...
LILACS
LIS