The epidemiology of sepsis in a Brazilian teaching hospital
Braz. j. infect. dis
;
14(3): 264-270, May-June 2010. ilus, tab
Article
in English
| LILACS
| ID: lil-556839
ABSTRACT
OBJECTIVES:
The objective of this study was to estimate disease incidence and mortality rate of sepsis in a tertiary public hospital.METHODS:
Patients admitted to the Intensive Care Unit (ICU) in 2004 and 2005 were monitored for sepsis using an observational longitudinal study design. Patients were monitored daily for diagnostic criteria of sepsis, according to ACCP/SCCM Consensus Conference criteria, until either death or hospital discharge.RESULTS:
During the study, we analyzed 1,179 patients. Systemic Inflammatory Response Syndrome (SIRS) was present in 1,048 (88.9 percent) patients on admission, and was associated with infection in 554 (47.0 percent) patients. Of these, sepsis was diagnosed in 30 (2.5 percent) patients, while severe sepsis was diagnosed in 269 (22.8 percent) patients, and septic shock was diagnosed in 255 (21.6 percent) patients. APACHE II and SOFA scores were higher in septic patients (p < 0.001), and the ensuing mortality rates were 32.8 percent (IC 95 percent 21.6-45.7 percent) for patients with sepsis, 49.9 percent (IC 95 percent 44.5-55.2 percent) for severe sepsis, and 72.7 percent (IC 95 percent 68.1-76.9 percent) for septic shock.CONCLUSIONS:
The data from our study revealed a high incidence of sepsis among hospitalized patients. Moreover, sepsis patients had a high rate of mortality.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Hospital Mortality
/
Sepsis
Type of study:
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2010
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital Universitário de Londrina/BR
/
Universidade Estadual de Londrina/BR
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