Risk factors related to hypertension among patients in a cohort living with HIV/AIDS
Braz. j. infect. dis
;
14(3): 281-287, May-June 2010. ilus, tab
Article
in English
| LILACS
| ID: lil-556842
ABSTRACT
INTRODUCTION:
Studies disagree as to whether there is a greater prevalence of hypertension among HIV/AIDS patients and the role of antiretroviral therapy.OBJECTIVE:
Evaluate the prevalence of hypertension and risk factors in a cohort of HIV-infected patients, with emphasis on antiretroviral therapy.METHOD:
Case-control study conducted at baseline of a cohort, between June/2007 and December/2008 in Pernambuco/Brazil. Blood pressure was classified as normal, prehypertension, and hypertension.RESULTS:
Of 958 patients, 245 (25.6 percent) had hypertension (cases), 325 (33.9 percent) had prehypertension, and 388 (40.5 percent) were normotensive (controls). Comparison between hypertensive and normotensive patients showed that traditional factors, such as age > 40 (OR = 3.06, CI = 1.91-4.97), male gender (OR = 1.85, CI = 1.15-3.01), BMI > 25 (OR = 5.51, CI = 3.36-9.17), and triglycerides > 150 mg/dL (OR = 1.69, CI = 1.05-2.71), were independently associated with hypertension. Duration of antiretroviral therapy and CD4 > 200 cells/mm³ were associated with hypertension in univariate analysis, but did not remain in final model. Type of antiretroviral schema and lipodystrophy showed no association with hypertension.CONCLUSION:
Hypertension in HIV/AIDS patients is partially linked to invariable factors, such as age and sex. Efforts should be directed toward controlling reversible factors, particularly excessive weight gain and unsuitable diet.
Full text:
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Index:
LILACS (Americas)
Main subject:
HIV Infections
/
Anti-HIV Agents
/
Hypertension
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2010
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Ministry of Health/BR
/
Universidade Federal da Paraíba/BR
/
Universidade Federal de Pernambuco/BR
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