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Prevalencia de anticuerpos contra Brucella sp. En donantes del banco de sangre de un hospital de Lima / Prevalence of antibodies against brucella sp of donors from hospital blood bank of Lima
Ortega C., Abel; Paredes A., José; Guillén, Alfredo.
  • Ortega C., Abel; Universidad Nacional Mayor de San Marcos. Facultad de Medicina. Lima. PE
  • Paredes A., José; Hospital Edgardo Rebagliati Martins. Banco de Sangre. Lima. PE
  • Guillén, Alfredo; Clínica Javier Prado. Laboratorio Clínico. Lima. PE
Rev. peru. med. exp. salud publica ; 24(4): 431-434, oct.-dic. 2007. ilus, tab
Article in Spanish | LILACS, LIPECS | ID: lil-559313
RESUMEN
El Perú es un país endémico de Brucelosis, por lo que existe el riesgo de transmisión a través de sangre donada por no ser parte del tamizaje regular que realizan los bancos de sangre. Para conocer la prevalencia de anticuerpos contra Brucella en donantes del banco de sangre del Hospital Edgardo Rebagliati Martins, se analizó 1003 muestras de suero. La prueba tamiz fue Rosa de Bengala (RB); las muestras positivas fueron evaluadas por las pruebas de aglutinación en tubo (AT) y 2-Mercaptoetanol (2-ME). Dos donantes fueron positivos a RB, confirmados por AT y 2-ME, se encontró una prevalencia de 0,20 por ciento (IC99 por ciento 0,01-0,92). Se demostró la presencia de donantes portadores de anticuerpos contra Brucella con posible Brucelosis activa, evidenciándose la posibilidad de transmisión de esta infección. Se debe realizar mayores estudios con la finalidad de conocer la realidad de otros bancos de sangre.
ABSTRACT
Peru is an endemic country for Brucellosis, consequently, there is a risk of transmission through donated blood, by not to be part of regular screening carried out by blood banks. To determine the prevalence of antibodies against Brucella in the donor blood bank from Edgardo Rebagliatti Martins Hospital (Lima, Peru), were analyzed 1003 samples of blood donors. The screening was Rose Bengal test (RB); the positive samples were evaluated by tube agglutination test (AT) and 2-mercaptoethanol test (2-ME). Two donors were positives to RB, and confirmed by AT and 2-ME, was found a prevalence of 0.20 per cent (99 per cent CI 0.10-0.92). It showed the presence of carrier donors of anti-Brucella antibodies with possible active brucellosis, was demonstrated, being evidenced the possibility to infection transmission. More studies have to be made to know the reality in other blood banks.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Blood Banks / Blood Transfusion / Brucellosis / Prevalence / Risk Factors / Donor Selection / Hemotherapy Service Type of study: Etiology study / Observational study / Prevalence study / Risk factors / Screening study Limits: Humans Language: Spanish Journal: Rev. peru. med. exp. salud publica Year: 2007 Type: Article Institution/Affiliation country: Clínica Javier Prado/PE / Hospital Edgardo Rebagliati Martins/PE / Universidad Nacional Mayor de San Marcos/PE

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Full text: Available Index: LILACS (Americas) Main subject: Blood Banks / Blood Transfusion / Brucellosis / Prevalence / Risk Factors / Donor Selection / Hemotherapy Service Type of study: Etiology study / Observational study / Prevalence study / Risk factors / Screening study Limits: Humans Language: Spanish Journal: Rev. peru. med. exp. salud publica Year: 2007 Type: Article Institution/Affiliation country: Clínica Javier Prado/PE / Hospital Edgardo Rebagliati Martins/PE / Universidad Nacional Mayor de San Marcos/PE