Transfusão de plaquetas: do empirismo ao embasamento científico / Platelet transfusion: from empiricism to scientific evidence
Rev. bras. hematol. hemoter
;
32(4): 335-336, 2010.
Article
in Portuguese
| LILACS
| ID: lil-561360
ABSTRACT
Despite major advances in Brazilian blood transfusion therapy with a growing number of scientific publications, an increased number of repeat donors and a decline in serological ineligibility, a lack of conformity in the application of pre-transfusion tests that may compromise transfusion safety is still observed at transfusion agencies in the fringes of the blood transfusion therapy system. Additionally, although high rates of platelet transfusion refractoriness and significant rates of alloimmunization have been demonstrated in the international literature, few Brazilian centers have been concerned with the study of platelet alloimmunization and even fewer centers have evaluated the efficacy of platelet concentrate transfusion. As more than one million Brazilians, including many repeat blood donors, are listed in the National Bone Marrow Donor Registry (Redome), why not grant transfusion therapy services access to the HLA typing of these blood and marrow donors after obtaining their consent? And why not make use of the Redome data to evaluate the HLA compatibility of donors for alloimmunized patients who are candidates for bone marrow transfusion and who have already been typed? These measures, together with the identification of ABO and HPA antigens, will permit a complete assessment of platelet immunology, will guarantee the transfusion safety of this blood component, and will put Brazil at the same level as the so-called developed countries in terms of transfusion medicine.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Blood Platelets
/
Hemoglobins
/
Platelet Transfusion
Limits:
Humans
Language:
Portuguese
Journal:
Rev. bras. hematol. hemoter
Journal subject:
Hematology
Year:
2010
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual de Campinas/BR
/
Universidade Federal do Triângulo Mineiro/BR
Similar
MEDLINE
...
LILACS
LIS