Efeitos do etanol sobre a migração neuronal na formação do neocórtex cerebral / Effects of ethanol on the neuronal migration in the brain neocortex formation
Biosci. j
;
21(1): 151-157, Jan.-Apr. 2005.
Article
in Portuguese
| LILACS
| ID: lil-561933
RESUMO
Os neurônios migram das zonas ventriculares e subventriculares, através das glias radial e tangencial, para formar as várias camadas corticais do neocórtex adulto. A exposição crônica de ratas grávidas ao etanol desencadeia ectopia, heterotopia e despopulação neuronial, promovendo a chamada síndrome alcóolica fetal. O tratamento agudo de ratas grávidas na data de nascimento dos neurônios também promove efeitos graves na formação do neocórtex.
ABSTRACT
The neurons migrate from the ventricular and subventricular zones, through the radial and tangential glia, to form the several cortical shells of the adult neocortex. The chronic exposure to ethanol of pregnant female rats causes ectopia, heterotopia and neuronal depopulation, producint the fetal alcoholic syndrome. The acute exposure of pregnant female rats at the neurons birth time also promotes severe effects on the neocortex formation.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Cerebellar Cortex
/
Neocortex
/
Alcohol-Induced Disorders, Nervous System
/
Ethanol
/
Fetal Alcohol Spectrum Disorders
Limits:
Adult
/
Animals
/
Humans
/
Pregnancy
Language:
Portuguese
Journal:
Biosci. j
Year:
2005
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de Uberlândia/BR
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