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Avaliação do risco cardiovascular por meio do índice LAP em pacientes não obesas com síndrome dos ovários policísticos / Evaluation of cardiovascular risk by the LAP index in non-obese patients with polycystic ovary syndrome
Costa, Eduardo Caldas; Sá, Joceline Cássia Ferezini de; Soares, Elvira Maria Mafaldo; Lemos, Telma Maria Araújo Moura; Maranhão, Técia Maria de Oliveira; Azevedo, George Dantas.
  • Costa, Eduardo Caldas; s.af
  • Sá, Joceline Cássia Ferezini de; s.af
  • Soares, Elvira Maria Mafaldo; s.af
  • Lemos, Telma Maria Araújo Moura; s.af
  • Maranhão, Técia Maria de Oliveira; s.af
  • Azevedo, George Dantas; s.af
Arq. bras. endocrinol. metab ; 54(7): 630-635, Oct. 2010. graf, tab
Article in Portuguese | LILACS | ID: lil-564068
RESUMO

OBJETIVO:

Analisar o risco cardiovascular de mulheres não obesas com síndrome dos ovários policísticos (SOP) por meio do índice LAP (lipid accumulation product). SUJEITOS E

MÉTODOS:

283 pacientes (18-34 anos) alocadas do Hospital Universitário da Universidade Federal do Rio Grande do Norte, Natal-RN, foram divididas em quatro grupos 1) SOP magras (n = 35); 2) saudáveis magras (n = 162); 3) SOP com sobrepeso (n = 28); 4) saudáveis com sobrepeso (n = 58).

RESULTADOS:

Pacientes com SOP apresentaram valores superiores do índice LAP em comparação às saudáveis magras (22,26 vs. 15,87 cm.mmol/L; p = 0,007); sobrepeso (40,83 vs. 26,32 cm.mmol/L; p = 0,001). O percentual de mulheres acima do percentil 75 do índice LAP também foi superior nos subgrupos com SOP magras (17,1 vs. 6,8 por cento; p = 0,04); sobrepeso (37,5 vs. 13,8 por cento; p = 0,01).

CONCLUSÕES:

Na amostra estudada, as pacientes com SOP apresentaram maior risco cardiovascular avaliado pelo índice LAP, quando comparadas a mulheres saudáveis, mesmo na ausência de obesidade.
ABSTRACT

OBJECTIVE:

To analyze the cardiovascular risk of non-obese women with polycystic ovary syndrome (PCOS) by the LAP index (lipid accumulation product). SUBJECTS AND

METHODS:

283 patients (18-34 years) assigned at the University Hospital of the Federal University of Rio Grande do Norte, Natal-RN, were divided into four groups 1) lean PCOS (n = 35); 2) healthy lean (n = 162); 3) overweight PCOS (n = 28); 4) healthy overweight (n = 58).

RESULTS:

Patients with PCOS showed higher values of the LAP index than healthy controls lean (22.26 vs. 15.87 cm.mmol/L; p = 0.007); overweight (40.83 vs. 26.32 cm.mmol/L; p = 0.001). The percentage of women above the 75th percentile of the LAP index was also higher in the subgroups with PCOS lean (17.1 vs. 6.8 percent; p = 0.04); overweight (37.5 vs. 13.8 percent; p = 0.01).

CONCLUSIONS:

In our sample, patients with PCOS showed higher cardiovascular risk assessed by the LAP index in relation to healthy women, even in the absence of obesity.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Polycystic Ovary Syndrome / Triglycerides / Cardiovascular Diseases / Waist Circumference / Obesity Type of study: Etiology study / Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Female / Humans Language: Portuguese Journal: Arq. bras. endocrinol. metab Journal subject: Endocrinology / Metabolism Year: 2010 Type: Article

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Full text: Available Index: LILACS (Americas) Main subject: Polycystic Ovary Syndrome / Triglycerides / Cardiovascular Diseases / Waist Circumference / Obesity Type of study: Etiology study / Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Female / Humans Language: Portuguese Journal: Arq. bras. endocrinol. metab Journal subject: Endocrinology / Metabolism Year: 2010 Type: Article