Drug hypersensitivity in students from São Paulo, Brazil
Clinics
;
65(10): 1009-1011, 2010. tab
Article
in English
| LILACS
| ID: lil-565985
ABSTRACT
BACKGROUND:
Drug hypersensitivity is responsible for substantial mortality and morbidity, and increased health costs. However, epidemiological data on drug hypersensitivity in general or specific populations are scarce.METHODS:
We performed a cross-sectional survey of 1015 university students, using a self-reported questionnaire.RESULTS:
The prevalence of self-reported drug hypersensitivity was 12,11 percent (123/1015). The most frequently implicated drugs were non-steroidal anti-inflammatory drugs (45,9 percent) and beta-lactam and sulfonamide antibiotics (25,40 percent). The majority of the patients reported dermatological manifestations (99), followed by respiratory (40), digestive (23) and other (19). Forty-five patients had an immediate type reaction, and 76,72 percent (89) had the drug by oral route.CONCLUSION:
The results showed that drug hypersensitivity is highly prevalent in university students, and that nonsteroidal anti-inflammatory drug and antibiotics (beta-lactams and sulfonamide) are the most frequently concerned drugs.
Full text:
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Index:
LILACS (Americas)
Main subject:
Students
/
Drug Hypersensitivity
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Clinics
Journal subject:
Medicine
Year:
2010
Type:
Article
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