Adhesivo tisular 2-octil cianoacrilato en el cierre de enterotomía comparado con sutura manual tradicional en dos capas: modelo en perros / Comparison of 2-octyl cyanoacrylate adhesive and suturing for wound closure in the canine small bowel model
Cir. & cir
;
77(2): 121-125, mar.-abr. 2009. ilus, graf, tab
Article
in Spanish
| LILACS
| ID: lil-566647
RESUMEN
Objetivo: Saber si el adhesivo tisular 2-octil cianoacrilato da mejores resultados en el cierre de enterotomía en comparación con la sutura manual tradicional en dos capas. Material y métodos: Estudio comparativo experimental en 10 perros. A cada uno se le realizó dos enterotomías: a una se le aplicó adhesivo tisular 2-octil cianoacrilato y a la otra, sutura en dos capas con seda y catgut crómico. Se analizaron ocho variables. Resultados: El tiempo de cierre y el número de macrófagos fueron menores con el adhesivo tisular, encontrando diferencia estadísticamente significativa. En las otras seis variables estudiadas (adherencias, dehiscencia, peritonitis, diámetro luminal del intestino, fibrosis y tipo de inflamación) no hubo diferencias. Conclusiones: En este modelo, el adhesivo tisular 2-octil cianoacrilato fue igual de seguro que la sutura tradicional en dos capas con catgut crómico y seda para cierre de una enterotomía de intestino delgado.
ABSTRACT
OBJECTIVE: We undertook this study to evaluate 2-octyl cyanoacrylate (2OCA) glue and suture for wound closure in the small bowel. METHODS: This was a comparative and experimental study. Male and female domestic dogs (n = 10) underwent a 2.0-cm small bowel closure of two wounds. All of these had closure with 2OCA in the first wound. The controls (second wound in the same dog) were closed with suture. Four weeks later the wounds were observed to evaluate the repair. RESULTS: Wound closure time and macrophage count were lower with the 2OCA glue than in the suture group. CONCLUSIONS: 2OCA glue has the strength to seal a small bowel wound. The inflammatory response to the glue is less than that of the suture at 4 weeks. These properties may make it a suitable material for replacing suture in a small bowel wound.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tissue Adhesives
/
Wound Healing
/
Suture Techniques
/
Cyanoacrylates
/
Intestine, Small
Type of study:
Prognostic study
Limits:
Animals
Language:
Spanish
Journal:
Cir. & cir
Journal subject:
General Surgery
Year:
2009
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Escuela Médico Militar/MX
/
Hospital Central Militar/MX
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