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Screening of medicinal plants for antibacterial activities on Staphylococcus aureus strains isolated from bovine mastitis / Screening de plantas medicinais com atividade antimicrobiana contra cepas de Staphylococcus aureus isoladas de mastite bovina
Diaz, Marisa A. N; Rossi, Ciro C; Mendonça, Vítor R; Silva, Danielle M; Ribon, Andréa de O. B; Aguilar, Ananda P; Muñoz, Gaspar D.
  • Diaz, Marisa A. N; s.af
  • Rossi, Ciro C; s.af
  • Mendonça, Vítor R; s.af
  • Silva, Danielle M; s.af
  • Ribon, Andréa de O. B; s.af
  • Aguilar, Ananda P; s.af
  • Muñoz, Gaspar D; s.af
Rev. bras. farmacogn ; 20(5): 724-728, Oct.-Nov. 2010. tab
Article in English | LILACS | ID: lil-567414
ABSTRACT
Staphylococcus aureus is the main causative agent of bovine mastitis. The activity of several extracts from ten medicinal plants traditionally used in Brazil as antiseptic was investigated against fifteen strains of Staphylococcus aureus isolated from animals with mastitis manifestation by the disc diffusion method and broth microdilution assay. The interference of the extracts on cell in the form of adherent colonies was also evaluated. MIC values ranged from 0.5 mg/mL to 1.0 mg/mL and biofilm inhibitory concentration (BIC) were between 0.25 mg/mL and 0.8 mg/mL. Results revealed the potential of extracts of Senna macranthera, Artemisia absinthium, Cymbopogon nardus and Baccharis dracunculifolia as antibacterial agents against S. aureus strains isolated from bovine mastitis and support the possible use of these phytotherapic agents in the clinical management of the disease.
RESUMO
Staphylococcus aureus é o principal agente causador de mastite bovina. A atividade de diversos extratos de dez plantas medicinais tradicionalmente usadas no Brasil como anti-sépticas foi investigada contra quinze cepas de Staphylococcus aureus isoladas de animais com manifestação de mastite pelo método de difusão em ágar e ensaio de microdiluição. A interferência dos extratos na célula bacteriana em forma de colônias aderidas também foi avaliada. Os valores de MIC variaram de 0.5 mg/mL a 1.0 mg/mL e a concentração inibitória de biofilme (BIC) variou de 0.25 mg/mL a 0.8 mg/mL. Os resultados revelaram o potencial dos extratos de Senna macranthera, Artemisia absinthium, Cymbopogon nardus e Baccharis dracunculifolia como agentes antibacterianos contra cepas de S. aureus isolados de mastite bovina e suportam o possível uso destas plantas no manejo clínico da doença.

Full text: Available Index: LILACS (Americas) Type of study: Diagnostic study / Screening study Language: English Journal: Rev. bras. farmacogn Journal subject: Pharmacy Year: 2010 Type: Article

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Full text: Available Index: LILACS (Americas) Type of study: Diagnostic study / Screening study Language: English Journal: Rev. bras. farmacogn Journal subject: Pharmacy Year: 2010 Type: Article