Translocación bacteriana e infecciones en un modelo experimental de cirrosis en la rata / Bacterial translocation and infections in an experimental model
Gastroenterol. latinoam
;
21(2): 234-236, abr.-jun. 2010. tab
Article
in English
| LILACS
| ID: lil-570014
ABSTRACT
In summary the carbon tetrachloride/phenobarbital of cirrhosis in rats mimics human cirrhosis very closely, with development of ascites and SBP. This model shows us that bacterial overgrowth occurs as cirrhosis progresses and that bacterial translocation from the gut to extra-intestinal sites is part of the early pathogenesis of SBP. SID with norfloxacin dramatically reduced translocation and SBP at the expense of grampositive overgrowth and infection with gram-positives and colonization with strange gram negatives. SID with TMP-SMZ actually delayed development of ascites and prolonged survival.
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Index:
LILACS (Americas)
Main subject:
Peritonitis
/
Ascites
/
Bacterial Translocation
/
Liver Cirrhosis, Experimental
Limits:
Animals
Language:
English
Journal:
Gastroenterol. latinoam
Journal subject:
Gastroenterology
Year:
2010
Type:
Article
Affiliation country:
United States
Institution/Affiliation country:
University of Loma Linda/US
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