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IMC, deficit cognitivo e sintomas depressivos em pacientes de alto risco cardiovascular / Body mass index, cognitive deficit and depressive symptoms in high cardiovascular risk patients
Costa, Amanda Lucas da; Varela, Juliana Santos; Cruz, Matheus Roriz; Costa, Andry Fitterman; Picon, Paulo Dornelles; Moriguch, Emilio; Chaves, Márcia L. F.
  • Costa, Amanda Lucas da; Hospital de Clínicas de Porto Alegre. Neurology Service. Dementia Clinic. Porto Alegre. BR
  • Varela, Juliana Santos; Hospital de Clínicas de Porto Alegre. Neurology Service. Dementia Clinic. Porto Alegre. BR
  • Cruz, Matheus Roriz; Federal University of Rio Grande do Sul. School of Medicine. Medical Sciences Post-Graduation Course. Porto Alegre. BR
  • Costa, Andry Fitterman; Hospital de Clínicas de Porto Alegre. Dyslipidemia and High Cardiovascular Risk Clinic. Porto Alegre. BR
  • Picon, Paulo Dornelles; Hospital de Clínicas de Porto Alegre. Dyslipidemia and High Cardiovascular Risk Clinic. Porto Alegre. BR
  • Moriguch, Emilio; Hospital de Clínicas de Porto Alegre. Dyslipidemia and High Cardiovascular Risk Clinic. Porto Alegre. BR
  • Chaves, Márcia L. F; Federal University of Rio Grande do Sul. School of Medicine. Hospital de Clínicas de Porto Alegre. Neurology Service. Dementia Clinic. Porto Alegre. BR
Dement. neuropsychol ; 4(4)dez. 2010.
Article in English | LILACS | ID: lil-570181
ABSTRACT
To evaluate the relationship of obesity, cognitive impairment and depressive symptoms in patients with high cardiovascular risk.

Methods:

A sample of 93 patients aged 50 years or older was selected from the Center of Dyslipidemia and High Cardiovascular Risk from Hospital de Clínicas de Porto Alegre (HCPA). Patients with stroke were excluded. For cognitive evaluation, the MMSE (Mini Mental State Examination) was used. A score of 24 or less was considered as cognitive impairment, and for those who had 4 years or less of education, the cutoff point was 17. The GDS-15 (Geriatric Depression Scale) was also used, with the cutoff of 6 for presence of depressive symptoms.

Results:

Obese patients showed lower mean MMSE scores compared to non-obese patients (p=0.0012). Additionally, for every one point increase in BMI above 30 there was a 27% increase in the chances of the patient having cognitive impairment. The obese patients presented 31% chance of having cognitive impairment compared with overweight subjects.

Conclusions:

Our findings corroborated the association between obesity and cognitive impairment in high cardiovascular risk patients. This association however, was not observed for depressive symptoms.
RESUMO
Avaliar a associação entre obesidade, comprometimento cognitivo e sintomas depressivos em pacientes de alto risco cardiovascular.

Métodos:

Foi selecionada uma amostra de 93 pacientes com 50 anos ou mais em acompanhamento no Centro de Dislipidemia e Alto Risco Cardiovascular do Hospital de Clínicas de Porto Alegre (HCPA). Pacientes com história de acidente vascular cerebral (AVC) foram excluídos. Para a avaliação cognitiva, foi utilizado o MEEM (Mini Exame do Estado Mental). Escores de 24 ou menos foram considerados como comprometimento cognitivo, para pacientes com 4 ou menos anos de escolaridade, o ponto de corte usado foi de 17 pontos. A escala GDS-15 (Geriatric Depression Scale) também foi utilizada, sendo adotado o ponto de corte 6 para a presença de sintomas depressivos.

Resultados:

Pacientes obesos apresentaram valores menores na média dos escores do MEEM quando comparados a pacientes não-obesos (p=0,0012). Além disso, para cada ponto de acréscimo no IMC acima de 30, houve um aumento de 27% na chance do paciente ter comprometimento cognitivo. Os pacientes obesos apresentaram 31% de chance de ter comprometimento cognitivo quando comparados com pacientes com sobrepeso.

Conclusões:

Os achados do presente estudo corroboram a associação entre obesidade e comprometimento cognitivo em pacientes de alto risco cardiovascular. Entretanto, esta associação não foi observada ao se analisar os sintomas depressivos.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Cardiovascular Diseases / Cognition / Stroke / Depression / Obesity Type of study: Diagnostic study / Etiology study / Evaluation studies / Risk factors Limits: Humans Language: English Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / Neurology / Psychology / Psychiatry Year: 2010 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Rio Grande do Sul/BR / Hospital de Clínicas de Porto Alegre/BR

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Full text: Available Index: LILACS (Americas) Main subject: Cardiovascular Diseases / Cognition / Stroke / Depression / Obesity Type of study: Diagnostic study / Etiology study / Evaluation studies / Risk factors Limits: Humans Language: English Journal: Dement. neuropsychol Journal subject: NEUROCIENCIAS / Neurology / Psychology / Psychiatry Year: 2010 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Rio Grande do Sul/BR / Hospital de Clínicas de Porto Alegre/BR