Inclusão de casca de pinhão-manso em dietas de ovinos: consumo voluntário e caracterização de quadro toxicológico / Fruit shell from jatropha curcas including in sheep diets: a nutritional assessment and toxicological characterization

ABSTRACT

The nutrients intake and histopathological occurrences were evaluated in sheep fed diets with increasing levels of inclusion (0%, 15%, 30%, and 45%) of Jatropha curcas dried and crushed fruit shell in substitution to Mombaça grass hay. Twenty castrated male sheep were kept in metabolic cages and fed diets ad libitum (5 to 10% scraps were allowed). At the end of the experiment, the animals were subjected to clinical examination and blood collection, followed by euthanasia and necropsy. The clinical and pathological disorders were characterized by digestive, lung, and heart alterations, with regressive changes affecting kidney and liver. Presence of fluid in the abdominal and pericardial cavities, intestine with little content or empty, reddish serosa, and hyperemic mucosa with streaks of blood were observed during necropsy; as well as edematous mesenteric lymph nodes; red, swollen, and firm lung (hepatization) with emphysema areas, suffusions in the serous of the rumen, and ulcers in the abomasum. Histopathological analysis revealed congestion and pulmonary edema, congestion and vacuolar degeneration of hepatocytes, edematous mesenteric lymph nodes, tubular degeneration, and the presence of calcium crystals in the kidney. Thus, the collected data reveals that J. curcas fruit shell is toxic when added at different levels in sheep diet.