Biological activity of the aqueous extract of Lychnophora pinaster Mart.

Silveira, D; Wagner, H; Chiari, E; Lombardi, J. A; Assunção, A. C; Oliveira, A. B. de; Raslan, D. S

Silveira, D; Wagner, H; Chiari, E; Lombardi, J. A; Assunção, A. C; Oliveira, A. B. de; Raslan, D. S.

Affiliation

Silveira, D; s.af
Wagner, H; s.af
Chiari, E; s.af
Lombardi, J. A; s.af
Assunção, A. C; s.af
Oliveira, A. B. de; s.af
Raslan, D. S; s.af

Rev. bras. farmacogn ; 15(4): 294-297, out.-dez. 2005. tab

Article in En | LILACS | ID: lil-570932

Responsible library: BR1.1

ABSTRACT

ABSTRACT

Lyophilized aqueous extract (LAE) from Lychnophora pinaster Mart (Asteraceae) aerial parts was evaluated in the search of possible biological activities. LAE exhibited trypanocidal activity (113.62 mg/mL), but could not inhibit 5-lipoxygenase in vitro (17 percent of inhibition). LAE chemical characterization by HPLC with UV-Diode Array Detector showed the presence of caffeic acid, isochlorogenic acid, vitexin, isovitexin and quercetin, in comparison with authentic samples.

Key words

5-lipoxygenase assay; Lychnophora pinaster; Trypanocidal activity

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