Association of PPARgama2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population
Genet. mol. biol
;
34(1): 56-61, 2011. tab
Article
in English
| LILACS
| ID: lil-573709
ABSTRACT
The PPARγ2 gene is a key regulator of both proliferation and preadipocyte differentiation in mammals. Herein its genotype and allele frequencies were analyzed using PCR-SSCP in eight pig breeds (N = 416). Two kinds of polymorphisms of the PPARγ2 gene were detected, including a previously reported shift SNP A177G (Met59Val) in exon 1 and a novel silent mutation G876A in exon 5. The results revealed that European pig breeds carry a higher allele A frequency at the A177G locus and a fixed GG genotype at the G876A locus. Allele A at the G876A locus was only found in Jinhua pigs. The association between haplotype (A177G/G876A) and carcass and meat quality traits was analyzed in a Pietrain x Jinhua F2 population (N = 248). The PPARγ2 gene was found to be significantly associated with backfat thickness at the shoulder (p < 0.05), 6-7th ribs (p < 0.01), last rib (p < 0.01), gluteus medius (p <0.05) and ham weight (p < 0.01). Significant effects of different haplotypes on ham weight and backfat thickness at the 6-7th ribs, last rib, and gluteus medius were also observed.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Swine
/
Food Quality
/
PPAR gamma
Type of study:
Risk factors
Limits:
Animals
Language:
English
Journal:
Genet. mol. biol
Journal subject:
Genetics
Year:
2011
Type:
Article
/
Project document
Affiliation country:
China
Institution/Affiliation country:
Hangzhou Normal University/CN
/
Zhejiang University/CN
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