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Association of PPARgama2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population
Chen, Zhe; Zhao, Xiaofeng; Jiang, Xiaoling; Guo, Xiaoling; Lv, Zunzhou; Zhou, Hongmei; Xu, Ningying.
  • Chen, Zhe; Zhejiang University. College of Animal Science. CN
  • Zhao, Xiaofeng; Hangzhou Normal University. College of Life and Environmental Sciences. CN
  • Jiang, Xiaoling; Zhejiang University. College of Animal Science. CN
  • Guo, Xiaoling; Zhejiang University. College of Animal Science. CN
  • Lv, Zunzhou; Zhejiang University. College of Animal Science. CN
  • Zhou, Hongmei; Zhejiang University. College of Animal Science. CN
  • Xu, Ningying; Zhejiang University. College of Animal Science. CN
Genet. mol. biol ; 34(1): 56-61, 2011. tab
Article in English | LILACS | ID: lil-573709
ABSTRACT
The PPARγ2 gene is a key regulator of both proliferation and preadipocyte differentiation in mammals. Herein its genotype and allele frequencies were analyzed using PCR-SSCP in eight pig breeds (N = 416). Two kinds of polymorphisms of the PPARγ2 gene were detected, including a previously reported shift SNP A177G (Met59Val) in exon 1 and a novel silent mutation G876A in exon 5. The results revealed that European pig breeds carry a higher allele A frequency at the A177G locus and a fixed GG genotype at the G876A locus. Allele A at the G876A locus was only found in Jinhua pigs. The association between haplotype (A177G/G876A) and carcass and meat quality traits was analyzed in a Pietrain x Jinhua F2 population (N = 248). The PPARγ2 gene was found to be significantly associated with backfat thickness at the shoulder (p < 0.05), 6-7th ribs (p < 0.01), last rib (p < 0.01), gluteus medius (p <0.05) and ham weight (p < 0.01). Significant effects of different haplotypes on ham weight and backfat thickness at the 6-7th ribs, last rib, and gluteus medius were also observed.
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Full text: Available Index: LILACS (Americas) Main subject: Swine / Food Quality / PPAR gamma Type of study: Risk factors Limits: Animals Language: English Journal: Genet. mol. biol Journal subject: Genetics Year: 2011 Type: Article / Project document Affiliation country: China Institution/Affiliation country: Hangzhou Normal University/CN / Zhejiang University/CN

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Full text: Available Index: LILACS (Americas) Main subject: Swine / Food Quality / PPAR gamma Type of study: Risk factors Limits: Animals Language: English Journal: Genet. mol. biol Journal subject: Genetics Year: 2011 Type: Article / Project document Affiliation country: China Institution/Affiliation country: Hangzhou Normal University/CN / Zhejiang University/CN