Goldenhar syndrome: clinical features with orofacial emphasis
J. appl. oral sci
;
18(6): 646-649, Nov.-Dec. 2010. ilus
Article
in English
| LILACS
| ID: lil-573738
ABSTRACT
OBJECTIVES:
Goldenhar syndrome (GS) is a relatively common developmental disorder characterized by craniofacial anomalies in association with vertebral, cardiac, renal, and central nervous system defects. This paper describes GS features with special emphasis on oral characteristics. MATERIAL ANDMETHODS:
The clinical features of 6 patients with GS aged 3 months to 12 years are described, and a brief review of the literature about this genetic disorder is presented.RESULTS:
All patients demonstrated the classical triad of GS, including mandibular hypoplasia resulting in facial asymmetry, ear and/or eye malformation, and vertebral anomalies. In addition, renal and gastrointestinal abnormalities were observed in 2 patients. Regarding the oral involvement, 2 patients presented cleft lip and palate, and 1 patient had temporomandibular joint malformation. Malocclusion was found in all patients.CONCLUSION:
Our orofacial findings correlate with the reported cases in the literature, and point out that after diagnosis GS patients need to be examined for systemic abnormalities.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Maxillofacial Abnormalities
/
Facial Asymmetry
/
Goldenhar Syndrome
Type of study:
Etiology study
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2010
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
State University of Campinas/BR
/
State University of Montes Claros/BR
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