Biologia molecular: aspectos básicos da genética: parte I / Molecular biology: genetic basic aspects: part I
Femina
;
38(11): 575-582, nov. 2010. tab
Article
in Portuguese
| LILACS
| ID: lil-575017
RESUMO
A presente revisão pretende analisar os mais recentes métodos existentes na Biologia molecular-genética médica, com direcionamento quanto à detecção e ao acompanhamento das diferentes neoplasias ginecológicas. Inicialmente, neste estudo serão discutidos os aspectos básicos e as características celulares importantes, as diversas fases celulares e os métodos de análise existentes para avaliação dos cromossomos e dos genes. São revistos os mais importantes fatores oncogênicos responsáveis pela carcinogênese, bem como a ação dos oncogenes e dos genes supressores dos tumores.
ABSTRACT
This review intends to analyze the latest existing methods in Molecular Biology-Medical genetics, focusing on the detection and tracking of different gynecological neoplasias. This study will initially discusses basic aspects and important cellular characteristics, as well as the different cellular phases and existing analytical methods for the study of chromosomes and genes. It also reviews the most important oncogenic factors which are responsible for carcinogenesis, as well as the action of oncogenes and tumor-supressing factors.
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Index:
LILACS (Americas)
Main subject:
Oncogenes
/
Cell Cycle
/
Genes, Tumor Suppressor
/
Chromosomes
/
Genetics, Medical
/
Genital Neoplasms, Female
/
Molecular Biology
/
Mutation
Limits:
Female
/
Humans
/
Male
Language:
Portuguese
Journal:
Femina
Journal subject:
Gynecology
/
Obstetrics
Year:
2010
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal do Paraná/BR
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