Incidence of Trypanosoma cruzi transmission through breastfeeding during acute experimental Chagas disease
Braz. j. infect. dis
;
15(2): 116-118, Mar.-Apr. 2011. ilus
Article
in English
| LILACS
| ID: lil-582412
ABSTRACT
OBJECTIVE:
To verify the incidence of T. cruzi transmission through breastfeeding during acute experimental Chagas' disease.METHODS:
Fifteen female Swiss mice were mated and, after pregnancy confirmation, placed in individual cages. A few hours after birth, the females were inoculated with 0.1 mL of blood containing approximately 3 x 10(5) trypomastigote forms of Y strain of T. cruzi and continued breastfeeding for 25 days.RESULTS:
In 142 offspring examined no infection through breast-feeding was observed.CONCLUSIONS:
The low number of trypomastigote forms ingested by the newborn mice combined with biological and biochemical characteristics of blood trypomastigotes may explain the lack of transmission in this experiment.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Breast Feeding
/
Chagas Disease
/
Pregnancy Complications, Parasitic
Type of study:
Incidence study
/
Prognostic study
/
Risk factors
Limits:
Animals
/
Pregnancy
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2011
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Faculdade de Medicina de Marília/BR
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