Disfunções cognitivas em pacientes com hipotireoidismo subclínico / Cognitive dysfunction in patients with subclinical hypothyroidism
Arq. bras. endocrinol. metab
;
55(3): 224-228, abr. 2011. tab
Article
in Portuguese
| LILACS
| ID: lil-588895
RESUMO
OBJETIVO: Avaliar a presença de disfunções cognitivas em pacientes com hipotireoidismo subclínico (HS). SUJEITOS E MÉTODOS: Estudo seccional comparando os achados neuropsicológicos de 89 pacientes com HS e 178 indivíduos eutireoidianos. Para avaliação neuropsicológica, foram utilizados: Teste de Performance Contínua (CPT-II), Iowa Gambling Task, Teste de Stroop, Teste de Wisconsin (WCST), Teste da Figura Complexa de Rey-Osterreich, Teste de Fluência Verbal (categorias semântica e fonológica) e Teste de Aprendizagem Auditivo Verbal de Rey. RESULTADOS: Os pacientes mostraram pior desempenho na flexibilidade cognitiva (WCST) e na capacidade de manter atenção sustentada (erros por omissão no CPT-II). CONCLUSÕES: Esses déficits podem causar prejuízos na vida diária do paciente, constituindo possíveis indicações de tratamento.
ABSTRACT
OBJECTIVE: Evaluate neuropsychological changes in patients with subclinical hypothyroidism (SH). SUBJECTS AND METHODS: Cross-sectional study comparing the results of the neuropsychological evaluation of 89 SH patients and 178 individuals without thyroid disease. The participants underwent the following neuropsychological assessment: Conner's Continuous Performance Test (CPT-II), Iowa Gambling Task, Stroop Test, Wisconsin Card Sorting Test (WCST), Verbal Fluency Test (semantic and phonologic categories) and Rey Auditory Verbal Learning Test. RESULTS: Among the neuropsychological tests, patients showed worse performance only in cognitive flexibility (WCST) and the ability to maintain sustained attention (omission errors on the CPT-II). CONCLUSIONS: These losses can cause detriments in the daily lives of patients, constituting potential treatment indications.
Full text:
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Index:
LILACS (Americas)
Main subject:
Cognition Disorders
/
Hypothyroidism
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Portuguese
Journal:
Arq. bras. endocrinol. metab
Journal subject:
Endocrinology
/
Metabolism
Year:
2011
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Metropolitano de Ensino Superior/BR
/
Universidade Federal de Minas Gerais/BR
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