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Uso de una escala clínica predictiva para el diagnóstico de meningitis bacteriana en pediatría: [revisión] / Utility of a predictive score for the diagnosis of bacterial meningitis in children: [review]
Ruiz, Karla; Soave, Yanina; Torres, Mary; Alcalá, Nelson.
  • Ruiz, Karla; Hospital Doctor Jesús Yerena. VE
  • Soave, Yanina; Hospital Doctor Jesús Yerena. VE
  • Torres, Mary; Hospital Doctor Jesús Yerena. VE
  • Alcalá, Nelson; Hospital Doctor Jesús Yerena. VE
Arch. venez. pueric. pediatr ; 73(1): 14-19, ene.-mar. 2010. tab, graf
Article in Spanish | LILACS | ID: lil-589185
RESUMEN
La difícil interpretación de los hallazgos sugestivos de meningitis bacteriana y viral en el líquido cefalorraquídeo con frecuencia imposibilita su diferenciación. Por décadas, los investigadores han intentado crear escalas predictivas que permitan resolver tal disyuntiva. El objetivo del presente trabajo es determinar la validez y seguridad de una escala clínica predictiva para el diagnóstico de meningitis bacteriana en Pediatría. Realizamos un estudio retrospectivo, transversal, de evaluación de una prueba diagnóstica en una muestra de pacientes con edades entre 29 días y 12 años, egresados con diagnóstico de meningitis entre enero de 1992 y diciembre de 2006, del Deparatmento de Pediatría del Hospital "Dr. Jesús Yerena", ubicado en Caracas, Venezuela. aplicamos una escala clínica predictiva y calculamos su sensibilidad, especificidad, valores predictivos y razones de verosimilitud para el diagnóstico de meningitis bacteriana. La muestra estuvo conformada por 41 pacientes. Predomino el sexo masculino (n=29; 70,73 por ciento). El grupo etareo más afectado fue el de los lactantes menores (26=; 63,41 por ciento). Se identificaron 14 meningitis bacterianas y 27 asépticas. Mediante la escala clínica predictiva se clasificaron 31 meningitis como de alto riesgo de meningitis v¡bacteriana y 10 como de bajo riesgo. La sensibilidad y valor predictivo negativo fueron de 100 por ciento. La escala clínica predictiva resultó ser válida y segura para descartar meningitis bacteriana.
ABSTRACT
The overlapping of finding suggestive of bacterial or viral meningitis in cerebrospinal fluid makes it difficult to differentiate one of another. For decades, investigators have attempted to create clinical prediction scores to resolve such disjunctive. The objetive of this investigation was to determine the validity and safety of a clinical prediction score for the diagnosis of bacterial meningitis in childhood. We perfomed a retrospective, transversal, diagnosis test evaluation study of a sample of patients between 29 days to 12 years of age, dischanged from January 1992 to December 2006, with diagnosis of meningitis, from the Pediatrics Department of Dr. Jesús Yerena Hospital, in Caracas, Venezuela. The clinical prediction score was applied. We evaluated its validity and safety with the calculation of sensibility, specificity, predictive values and likelihood ratios for the diagnosis of bacterial meningitis. A total of 41 patients were included. Male gender was more common (n=29; 70,73%). The infant age group was predominant (n=26; 63,41%). We identified 14 bacterial meningitis and 27 aseptic meningitis. With the clinical predictin score, 31 meningitis were classified as high risk of bacterial meningitis and 10 as low risk. The sensibility and the negative value were 100%. The clinical prediction score applied resulted to be valid and safe for identifying patients without bacterial meningitis.
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Index: LILACS (Americas) Main subject: Meningitis, Bacterial / Ventriculoperitoneal Shunt / Meningitis, Aseptic / Anti-Bacterial Agents Type of study: Diagnostic study / Evaluation studies / Observational study / Prognostic study / Risk factors / Systematic reviews Limits: Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: Spanish Journal: Arch. venez. pueric. pediatr Journal subject: Pediatrics Year: 2010 Type: Article Affiliation country: Venezuela Institution/Affiliation country: Hospital Doctor Jesús Yerena/VE

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Index: LILACS (Americas) Main subject: Meningitis, Bacterial / Ventriculoperitoneal Shunt / Meningitis, Aseptic / Anti-Bacterial Agents Type of study: Diagnostic study / Evaluation studies / Observational study / Prognostic study / Risk factors / Systematic reviews Limits: Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: Spanish Journal: Arch. venez. pueric. pediatr Journal subject: Pediatrics Year: 2010 Type: Article Affiliation country: Venezuela Institution/Affiliation country: Hospital Doctor Jesús Yerena/VE