Polyoma BK virus: an emerging opportunistic infectious agent of the human central nervous system
Braz. j. infect. dis
;
15(3): 276-284, May-June 2011. tab
Article
in English
| LILACS
| ID: lil-589962
ABSTRACT
BK virus, a double-stranded DNA virus, is a member of the Polyomaviridae family which is known to infect humans. Clinical evidence of disease is mostly encountered in immunosuppressed individuals such as AIDS patients or those who undergo renal or bone marrow transplantation where complications associated with BKV infection manifest commonly as a polyomavirus nephropathy or hemorrhagic cystitis, respectively. Recent evidence suggests that in addition to the JC virus (the other member of the same family known to be strongly neurotropic and responsible for the progressive multifocal leukoencephalopathy), BK virus can infect and cause clinically relevant disease in the human central nervous system. In this mini-review, an analysis of the literature is made. A special focus is given to alert clinicians to the possibility of this association during the differential diagnosis of infections of the central nervous system in the immunocompromised host.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tumor Virus Infections
/
Opportunistic Infections
/
Central Nervous System Infections
/
BK Virus
/
Communicable Diseases, Emerging
/
Polyomavirus Infections
Type of study:
Diagnostic study
Limits:
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2011
Type:
Article
Affiliation country:
Portugal
Institution/Affiliation country:
CHLC/PT
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