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Diabetic ketoacidosis: difference between potassium determined by blood gas analysis versus plasma measurement / Cetoacidose diabética: diferença entre as concentrações do potássio na gasometria sanguínea versus potássio plasmático
Robles, Fernando César; Laguna Neto, Daniel; Dias, Fábio Guirado; Spressão, Márcia; Matos, Priscila Nascimbeni; Cordeiro, José Antônio; Pires, Antônio Carlos.
  • Robles, Fernando César; School of Medicine of São Jose do Rio Preto (Famerp). Departament of Endocrinology and Metabology. São Jose do Rio Preto. BR
  • Laguna Neto, Daniel; School of Medicine of São Jose do Rio Preto (Famerp). Departament of Endocrinology and Metabology. São Jose do Rio Preto. BR
  • Dias, Fábio Guirado; School of Medicine of São Jose do Rio Preto (Famerp). Departament of Endocrinology and Metabology. São Jose do Rio Preto. BR
  • Spressão, Márcia; School of Medicine of São Jose do Rio Preto (Famerp). Departament of Endocrinology and Metabology. São Jose do Rio Preto. BR
  • Matos, Priscila Nascimbeni; School of Medicine of São Jose do Rio Preto (Famerp). Departament of Endocrinology and Metabology. São Jose do Rio Preto. BR
  • Cordeiro, José Antônio; Famerp. Departament of Epidemiology and Collective Health. São Jose do Rio Preto. BR
  • Pires, Antônio Carlos; School of Medicine of São Jose do Rio Preto (Famerp). Departament of Endocrinology and Metabology. São Jose do Rio Preto. BR
Arq. bras. endocrinol. metab ; 55(4): 256-259, June 2011. ilus, tab
Article in English | LILACS | ID: lil-593117
ABSTRACT

OBJECTIVE:

To evaluate the accuracy of potassium concentrations measured by blood gas analysis (PBG) compared with laboratory serum potassium (LSP), in the initial care of patients with diabetic ketoacidosis (DKA). SUBJECTS AND

METHODS:

Fifty three patients with diabetes mellitus were evaluated in a retrospective analysis. PBG was carried out using the Radiometer ABL 700 (Radiometer Copenhagen®), and results were compared with LSP ADVIA 1650 Chemistry system (Siemens®), the gold standard method. Both methods are based on potentiometry.

RESULTS:

Mean PBG was 3.66 mmol/L and mean LSP was 4.79 mmol/L. Mean difference between PBG and LSP was -1.13 mmol/L (p < 0.0005, 95 percent CI, -1.39 to -0,86). Lin concordance correlation coefficient was rc = 0.28 (95 percent CIb, 0.10 to 0.45), demonstrating low concordance between the methods.

CONCLUSION:

Although PBG measurement is faster and easier, it should not be used as a surrogate for LSP in the clinical treatment of DKA.
RESUMO

OBJETIVO:

Avaliar a acurácia da mensuração da concentração de potássio realizado nos analisa-dores de gasometria sanguínea (PGS) em relação ao potássio plasmático laboratorial (PPL) no atendimento inicial dos pacientes com cetoacidose diabética (CAD). SUJEITOS E

MÉTODOS:

Foram avaliados, retrospectivamente, 53 pacientes com diabetes melito e CAD. A análise do PGS foi realizada pelo equipamento ABL 700 (Radiometer Copenhagen®), sendo este comparado ao método padrão-ouro de PPL ADVIA 1650 (Siemens®), ambos por potenciometria.

RESULTADOS:

A média do PGS foi de 3,66 mmol/L e do PPL, de 4,79 mmol/L. A diferença das médias do PGS em relação ao PPL foi de -1,13 mmol/L (p < 0,0005, IC = 95 por cento; -1,39 a -0,86). O coeficiente de concordância de Lin foi de rc = 0,28 (ICb = 95 por cento; 0,10 a 0,45), demonstrando, assim, uma baixa concordância entre os métodos.

CONCLUSÃO:

Apesar de a realização do PGS ser tecnicamente mais rápida e fácil, não deve ser usada como parâmetro substituto ao PPL para o tratamento clínico da CAD.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Potassium / Diabetic Ketoacidosis Type of study: Observational study Limits: Adolescent / Adult / Aged / Female / Humans / Male Language: English Journal: Arq. bras. endocrinol. metab Journal subject: Endocrinology / Metabolism Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: Famerp/BR / School of Medicine of São Jose do Rio Preto (Famerp)/BR

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Full text: Available Index: LILACS (Americas) Main subject: Potassium / Diabetic Ketoacidosis Type of study: Observational study Limits: Adolescent / Adult / Aged / Female / Humans / Male Language: English Journal: Arq. bras. endocrinol. metab Journal subject: Endocrinology / Metabolism Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: Famerp/BR / School of Medicine of São Jose do Rio Preto (Famerp)/BR