Histiocitosis de células de Langerhans pulmonar: Caso clínico / Adult pulmonary Langerhans cell histiocytosis: Report of one case
Rev. méd. Chile
;
139(2): 230-235, feb. 2011. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-595292
ABSTRACT
Adult pulmonary Langerhans cell histiocytosis (PLCH) is a rare disorder of unknown etiology that occurs predominantly in young smokers, with an incidence peak at 20-40 years of age. In adults, pulmonary involvement with Langerhans cell histiocytosis usually occurs as a single-organ disease and is characterized by focal Langerhans cell granulomas infiltrating and destroying distal bronchioles. We report a 23-year-old asymptomatic male smoker with a non specific interstitial infiltrate found in preventive chest X ray examination. A high resolution chest CT scan showed multiple cystic structures predominating in the upper lobes, with small centrilobular nodules. A transbronchial biopsy showed a lymphocytic lung infiltrate with Langerhans cells. A surgical biopsy confirmed the diagnosis of pulmonary Langerhans cell histiocytosis. After six months of follow up, the patient is in good conditions.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Histiocytosis, Langerhans-Cell
Limits:
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2011
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Regional de Antofagasta/CL
/
Pontificia Universidad Católica de Chile/CL
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