Spi2 gene polymorphism is not associated with recurrent airway obstruction and inflammatory airway disease in thoroughbred horses
Genet. mol. biol
;
34(3): 456-458, 2011. ilus, tab
Article
in English
| LILACS
| ID: lil-595981
ABSTRACT
The aim was to detect the presence of polymorphisms at exons 1, 2, 3 and 4 of the Spi2 gene, and evaluate a possible association between them and recurrent airway obstruction (RAO) or inflammatory airway disease (IAD) in thoroughbred horses, through single-strand conformational-polymorphism (SSCP) screening. Although polymorphism was not detected in exons 1, 2 and 3, three alleles and six genotypes were identified in exon 4. The frequencies of allele A (0.6388) and genotype AA (0.3888) were higher in horses affected by RAO, although no association was found between polymorphism and horses with either RAO or IAD.
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Index:
LILACS (Americas)
Main subject:
Polymorphism, Genetic
/
Respiratory Tract Diseases
/
Horses
Type of study:
Risk factors
Limits:
Animals
Language:
English
Journal:
Genet. mol. biol
Journal subject:
Genetics
Year:
2011
Type:
Article
Affiliation country:
Argentina
/
Brazil
Institution/Affiliation country:
Practitioner/AR
/
Universidade Federal de Santa Maria/BR
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