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Research of the origin of a particular Tunisian group using a physical marker and Alu insertion polymorphisms
Moncer, Wifak El; Bahri, Raoudha; Esteban, Esther; Abdenni-Guenounou, Bouthaina; Moral, Pedro; Chibani, Jemni Ben; Chaabani, Hassen.
  • Moncer, Wifak El; University of Monastir. Faculty of Pharmacy. Laboratory of Human Genetics and Anthropology. Monastir. TN
  • Bahri, Raoudha; University of Monastir. Faculty of Pharmacy. Laboratory of Human Genetics and Anthropology. Monastir. TN
  • Esteban, Esther; Universitat de Barcelona. Departament de Biologia Animal. Barcelona. ES
  • Abdenni-Guenounou, Bouthaina; Centre Régional de Transfusion Sanguine de Gabès. Gabès. TN
  • Moral, Pedro; Universitat de Barcelona. Departament de Biologia Animal. Barcelona. ES
  • Chibani, Jemni Ben; University of Monastir. Faculty of Pharmacy. Laboratory of Biochemistry. Monastir. TN
  • Chaabani, Hassen; University of Monastir. Faculty of Pharmacy. Laboratory of Human Genetics and Anthropology. Monastir. TN
Genet. mol. biol ; 34(3): 371-376, 2011. ilus, tab
Article in English | LILACS | ID: lil-595985
ABSTRACT
The aim of this study was to show how, in some particular circumstances, a physical marker can be used along with molecular markers in the research of an ancient people movement. A set of five Alu insertions was analysed in 42 subjects from a particular Tunisian group (El Hamma) that has, unlike most of the Tunisian population, a very dark skin, similar to that of sub-Saharans, and in 114 Tunisian subjects (Gabes sample) from the same governorate, but outside the group. Our results showed that the El Hamma group is genetically midway between sub-Saharan populations and North Africans, whereas the Gabes sample is clustered among North Africans. In addition, The A25 Alu insertion, considered characteristic to sub-Saharan Africans, was present in the El Hamma group at a relatively high frequency. This frequency was similar to that found in sub-Saharans from Nigeria, but significantly different from those found in the Gabes sample and in other North African populations. Our molecular results, consistent with the skin color status, suggest a sub-Saharan origin of this particular Tunisian group.
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Full text: Available Index: LILACS (Americas) Main subject: Polymorphism, Genetic / Population / Tunisia / Skin Pigmentation / Alu Elements Limits: Humans Country/Region as subject: Africa Language: English Journal: Genet. mol. biol Journal subject: Genetics Year: 2011 Type: Article Affiliation country: Spain / Tunisia Institution/Affiliation country: Centre Régional de Transfusion Sanguine de Gabès/TN / Universitat de Barcelona/ES / University of Monastir/TN

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Full text: Available Index: LILACS (Americas) Main subject: Polymorphism, Genetic / Population / Tunisia / Skin Pigmentation / Alu Elements Limits: Humans Country/Region as subject: Africa Language: English Journal: Genet. mol. biol Journal subject: Genetics Year: 2011 Type: Article Affiliation country: Spain / Tunisia Institution/Affiliation country: Centre Régional de Transfusion Sanguine de Gabès/TN / Universitat de Barcelona/ES / University of Monastir/TN