Bioactivity of the compounds isolated from Blepharocalyx salicifolius
Rev. bras. farmacogn
;
21(4): 645-651, jul.-ago. 2011. ilus, graf, tab
Article
in English
| LILACS
| ID: lil-596228
ABSTRACT
Blepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, is an endemic species that occurs at Southern America. This species was studied to intend to isolation of the active compounds that could be used in vitro model against leishmaniosis, tumoral cell and paracoccidioidomycosis. After Gel Permeation Chromatography, the ethanolic extract from leaves yielded sixteen fractions. Five compounds were isolated and assayed, showing activity against tumoral cells, from 3.33 to 12.83 µg.mL-1; Leishmania (Leishmania) amazonensis from 2.19 to 20.80 µg.mL-1 and Paracoccidioides brasiliensis from 3.10 to 12.5 µg.mL-1.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
Rev. bras. farmacogn
Journal subject:
Pharmacy
Year:
2011
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Centro de Pesquisa René Rachou/BR
/
Universidade Estadual do Sudoeste de Bahia/BR
/
Universidade Federal de Minas Gerais/BR
Similar
MEDLINE
...
LILACS
LIS