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Maternal Food Restriction During Lactation Reduces Mandible Growth of the Female Offspring in Adulthood: Experimental and Morphometric Analysis / Restricción Alimentaria Materna Durante la Lactancia Reduce el Crecimiento de la Mandíbula de las Crías Hembras en la Edad Adulta: Análisis Experimental y Morfométrico
Degani Junior, Hugo V. M; Nunes, Viviane A; Bezerra, Ewerton C; Ramos, Cristiane F; Rodrigues, Mauro R; Abidu-Figueiredo, Marcelo; Cardoso, Gilberto P; Babinski, Marcio A.
  • Degani Junior, Hugo V. M; Fluminense Federal University. Biomedical Center. Department of Morphology. BR
  • Nunes, Viviane A; Fluminense Federal University. Biomedical Center. Department of Morphology. BR
  • Bezerra, Ewerton C; Fluminense Federal University. Biomedical Center. Department of Morphology. BR
  • Ramos, Cristiane F; State University of Rio de Janeiro. Biomedical Center. Department of Anatomy. BR
  • Rodrigues, Mauro R; Fluminense Federal University. Biomedical Center. Department of Morphology. BR
  • Abidu-Figueiredo, Marcelo; Rural of Rio de Janeiro University. Department of Animal Anatomy. Rio de Janeiro. BR
  • Cardoso, Gilberto P; Fluminense Federal University. Biomedical Center. Department of Morphology. BR
  • Babinski, Marcio A; Fluminense Federal University. Biomedical Center. Department of Morphology. BR
Int. j. morphol ; 29(2): 598-603, June 2011. ilus
Article in English | LILACS | ID: lil-597499
ABSTRACT
The aim of this study was to evaluate the effects of maternal protein and energy restriction during lactation on mandible dimensions of pups (female) at aging. At parturition, Wistar rat dams were randomly assigned to the following groups 1) control group (C) - free access to a standard laboratory diet containing 23 percent protein, 2) protein-energy restricted group (PER) - free access to an isoenergetic, protein-restricted diet containing 8 percent protein, and 3) energy-restricted group (ER) ­ fed with restricted amounts of a standard laboratory diet. At weaning (d21), all pups were separated of dams and received free access to a standard laboratory diet containing 23 percent protein until 90 days (d90), when the rats were anesthetized and sacrificed. The dimensions of excised pup mandible were measured directly using pre-established 3 anatomical points. Morphometric analysis showed that most of the measurements in the ER and PER groups were significantly lower than in the control group, with the greatest reductions occurring in the PER group. These results show that protein and energy restriction during lactation have an important influence on pup mandible development and continue through the aging process.
RESUMEN
El objetivo de este estudio fue evaluar los efectos de la restricción de la proteína materna y de la energía durante la lactancia sobre las dimensiones de la mandíbula de crías (hembras) durante la vida. En el parto, las crías de ratas Wistar fueron agrupadas aleatoriamente en los siguientes grupos 1) control (C) - con acceso libre a una dieta estándar del laboratorio, que contenía 23 por ciento de proteínas; 2) con restriccion de proteínas y energía (PER) - acceso libre a una dieta isoenergética, con restricción de proteínas, conteniendo un 8 por ciento de éstas y 3) grupo con restricción de energía, alimentado con restricción en la cantidad de alimento de la dieta estándar del laboratorio (ER). Al destete, todas las crías fueron separadas y recibieron las dietas establecidas hasta los 90 días (d90), luego fueron anestesiadas y sacrificadas. Las mediciones de las mandíbulas de las crías de rata fueron obtenidas por 3 puntos anatómicos preestablecidos. El análisis morfométrico de la mandíbula demostró que la mayoría de las mediciones en los grupos ER y PER eran significativamente menores que las del grupo control, con mayores reducciones en el grupo PER. Estos resultados muestran que las restricciones de energía y proteínas durante la lactancia tienen una influencia importante en el desarrollo de la mandíbula de las crías, las que se mantuvieron con el paso del tiempo.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Diet, Protein-Restricted / Malnutrition / Mandible Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fluminense Federal University/BR / Rural of Rio de Janeiro University/BR / State University of Rio de Janeiro/BR

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Full text: Available Index: LILACS (Americas) Main subject: Diet, Protein-Restricted / Malnutrition / Mandible Limits: Animals Language: English Journal: Int. j. morphol Journal subject: Anatomy Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fluminense Federal University/BR / Rural of Rio de Janeiro University/BR / State University of Rio de Janeiro/BR