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Morphoquantitative study of the submucous plexus (of Meissner) of the jejunum-ileum of young and old guinea pigs / Estudo morfoquantitativo do plexo submucoso (de Meissner) do jejuno-íleo de cobaias jovens e velhas
Zanesco, Marcelo César; Souza, Romeu Rodrigues de.
  • Zanesco, Marcelo César; University of São Paulo. Institute of Biomedical Sciences. Department of Anatomy.
  • Souza, Romeu Rodrigues de; São Judas Tadeu University. Department of Anatomy. São Paulo. BR
Arq. neuropsiquiatr ; 69(1): 85-90, Feb. 2011. ilus, tab
Article in English | LILACS | ID: lil-598352
ABSTRACT

OBJECTIVE:

To study the aging of submucous plexus of the small intestine (jejunum-ileum) of the guinea pigs from the quantitative, structural and ultrastructural perspective.

METHOD:

Chemical preparations of membrane of the jejunum-ileum of old and young animals with the use of light and electronic microscope.

RESULTS:

The ganglia of young animals presented between 1 and 56 neurons and the old animals presented from 1 to 30 neurons. The mean density of the ganglia by cm² in the young jejunum-ileum was of 551±36.89 and in the old one 413±11.86. The density of the neurons was 5011±291.11 neurons/cm² average in young animals and 2918±120.70 neurons/cm² in the old ones. The size of the neurons varied in both age groups. The collagen fibers in the ganglia of old animals they were condensed. Degenerated mitochondrias in the interior of the cell were frequent in the old animals.

CONCLUSION:

In submucous plexus of the jejunum-ileum there is a loss of 38 percent of the neurons with aging.
RESUMO

OBJETIVO:

Estudar o envelhecimento do plexo submucoso do intestino delgado (jejuno-íleo) das cobaias do ponto de vista quantitativo, estrutural e ultra-estrutural.

MÉTODO:

Preparados de membrana do jejuno-íleo de animais jovens e velhos com a utilização de microscopia de luz e eletrônica.

RESULTADOS:

Os gânglios de animais jovens apresentaram entre 1 e 56 neurônios e os animais velhos apresentaram de 1 a 30 neurônios. A densidade média dos gânglios por cm² no jejuno-íleo jovem foi de 551±36,89 e no velho foi de 413±11,86. A densidade dos neurônios foi de 5011±291,11 neurônios/cm² em média nos animais jovens e 2918±120,70 neurônios/cm² nos velhos. O tamanho dos neurônios variou em ambos os grupos etários. As fibras colágenas nos gânglios de animais velhos estavam mais condensadas. Mitocôndrias degeneradas no interior da célula foram freqüentes nos animais velhos.

CONCLUSÃO:

No plexo submucoso do jejuno-íleo há uma perda de 38 por cento dos neurônios com o envelhecimento.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Submucous Plexus / Ileum / Jejunum / Neurons Limits: Animals Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: São Judas Tadeu University/BR

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Full text: Available Index: LILACS (Americas) Main subject: Submucous Plexus / Ileum / Jejunum / Neurons Limits: Animals Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: São Judas Tadeu University/BR