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In vitro adherence of Candida albicans isolated from patients with chronic periodontitis
Machado, Adriana Gadotti; Komiyama, Edson Yukio; Santos, Silvana Soléo Ferreira dos; Jorge, Antonio Olavo Cardoso; Brighenti, Fernanda Lourenção; Koga-Ito, Cristiane Yumi.
  • Machado, Adriana Gadotti; State University of São Paulo. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. São José dos Campos. BR
  • Komiyama, Edson Yukio; State University of São Paulo. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. São José dos Campos. BR
  • Santos, Silvana Soléo Ferreira dos; University of Taubaté. Department of Dentistry. Taubaté. BR
  • Jorge, Antonio Olavo Cardoso; State University of São Paulo. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. São José dos Campos. BR
  • Brighenti, Fernanda Lourenção; State University of São Paulo. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. São José dos Campos. BR
  • Koga-Ito, Cristiane Yumi; State University of São Paulo. São José dos Campos Dental School. Department of Biosciences and Oral Diagnosis. São José dos Campos. BR
J. appl. oral sci ; 19(4): 384-387, July-Aug. 2011. graf
Article in English | LILACS | ID: lil-599763
ABSTRACT
Adherence is considered an extremely important virulence factor in yeast.

OBJECTIVE:

The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND

METHODS:

Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted.

RESULTS:

The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000).

CONCLUSION:

The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.
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Full text: Available Index: LILACS (Americas) Main subject: Candida albicans / Epithelial Cells / Chronic Periodontitis Type of study: Observational study Limits: Adult / Humans Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: State University of São Paulo/BR / University of Taubaté/BR

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Full text: Available Index: LILACS (Americas) Main subject: Candida albicans / Epithelial Cells / Chronic Periodontitis Type of study: Observational study Limits: Adult / Humans Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2011 Type: Article Affiliation country: Brazil Institution/Affiliation country: State University of São Paulo/BR / University of Taubaté/BR