Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats
J. appl. oral sci
;
19(5): 500-504, Sept.-Oct. 2011. ilus, tab
Article
in English
| LILACS
| ID: lil-600840
ABSTRACT
OBJECTIVE:
This study evaluated experimentally-induced periapical bone loss sites using digital radiographic and histopathologic parameters. MATERIAL ANDMETHODS:
Twenty-seven Wistar rats were submitted to coronal opening of their mandibular right first molars. They were radiographed at 2, 15 and 30 days after the operative procedure by two digital radiographic storage phosphor plates (Digora®). The images were analyzed by creating a region of interest at the periapical region of each tooth (ImageJ) and registering the corresponding pixel values. After the sacrifice, the specimens were submitted to microscopic analysis in order to confirm the pulpal and periapical status of the tooth.RESULTS:
There was significant statistically difference between the control and test sides in all the experimental periods regarding the pixel values (two-way ANOVA; p<0.05).CONCLUSIONS:
The microscopic analysis proved that a periapical disease development occurred during the experimental periods with an evolution from pulpal necrosis to periapical bone resorption.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Periapical Diseases
/
Bone Resorption
/
Dental Pulp Necrosis
Type of study:
Evaluation studies
Limits:
Animals
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2011
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
University of São Paulo/BR
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