Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
Mem. Inst. Oswaldo Cruz
;
106(6): 777-780, Sept. 2011. tab
Article
in English
| LILACS
| ID: lil-602066
ABSTRACT
The performance of the immunochromatographic assay, SD BIOLINE TB Ag MPT64 RAPID®, was evaluated in Madagascar. Using mouse anti-MPT64 monoclonal antibodies for rapid discrimination between the Mycobacterium tuberculosis complex and nontuberculous mycobacteria, the kit was tested on mycobacteria and other pathogens using conventional methods as the gold standard. The results presented here indicate that this kit has excellent sensitivity (100 percent) and specificity (100 percent) compared to standard biochemical detection and can be easily used for the rapid identification of M. tuberculosis complex.
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Index:
LILACS (Americas)
Main subject:
Tuberculosis
/
Chromatography, Affinity
/
Bacterial Typing Techniques
/
Nontuberculous Mycobacteria
/
Mycobacterium tuberculosis
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Animals
/
Humans
Country/Region as subject:
Africa
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2011
Type:
Article
Affiliation country:
Burkina Faso
/
France
/
Madagascar
Institution/Affiliation country:
Institut Pasteur/MG
/
Ministère de la Santé/MG
/
Organisation Mondiale de la Santé/MG
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